GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule	Ligand Name	Ligand Feature	Target Source	Glycan Sequence	Binding	PubMed ID ▼
Escherichia coli	Unknown	Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH)	Oligoglycosylceramides	Vero cells	Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	15292153
Helicobacter pylori	BabA (blood group antigen binding adhesin)	Blood group Lewis b (Leb) antigen	Oligosaccharides			Binding	15273394
Helicobacter pylori	BabA (blood group antigen binding adhesin)	Blood group H1 antigen (HSA)	Glycoproteins		Fuc(a1-2)Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(c)-APD	Binding	15273394
Helicobacter pylori	BabA (blood group antigen binding adhesin)	Blood group B-Lewis b (BLeb) antigen	Oligosaccharides		Gal(a1-3)[Fuc(a1-2)]Gal(b1-3)[Fuc(a1-4)]GlcNAc	Binding	15273394
Helicobacter pylori	BabA (blood group antigen binding adhesin)	Blood group A-Lewis b (ALeb) antigen	Oligosaccharides		GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-3)[Fuc(a1-4)]GlcNAc	Binding	15273394
Helicobacter pylori	BabA (blood group antigen binding adhesin)	Blood group A antigen	Oligosaccharides		GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-3)GlcNAc	Binding	15273394
Parvovirus	Unknown	Sialic acid (both O- and N-linked)	Monosaccharides	Nucleated bovine cells		Binding	15269359
Treponema pallidum	Tp38 (TpMglB-2) lipoproteins	Glucose	Monosaccharides		Glc	Binding	15060032
Pseudomonas aeruginosa	PA-IL (51-kDa)	Melibiose	Disaccharides		Gal(a1-6)Glc	Binding	15049333
Pseudomonas aeruginosa	PA-IL (51-kDa)	Galactose-alpha-1,3-galactose	Disaccharides		Gal(a1-3)Gal	Binding	15049333