GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule	Ligand Name	Ligand Feature ▲	Target Source	Glycan Sequence	Binding	PubMed ID
Helicobacter pylori	Fibrillar hemmagglutinin	N-acetylneuraminyl-a(2-3)-galactopyranosyl sequence	Glycoproteins	Gastric epithelium, Mucus layer of the stomach	NeuAc(a2-3)Gal	Binding	2459065
Clostridium difficile	Toxin A	α-Gal on Fab of IgA(κ) MAb	Glycoproteins	Mouse	Gal	Binding	9573079
Clostridium difficile	Toxin A	α-Gal on Fab of IgM(λ) MAb	Glycoproteins	Mouse	Gal	Binding	9573079
Norovirus	Unknown	Blood group B antigen (B-tri-HSA)	Glycoproteins	Human serum albumin	Gal(a1-3)[Fuc(a1-2)]Gal(b)-O-APE	Binding	19054801
Norovirus	Unknown	Blood group A antigen (A-tri-HSA)	Glycoproteins	Human serum albumin	GalNAc(a1-3)[Fuc(a1-2)]Gal(b)-O-APE	Binding	19054801
Norovirus	Unknown	Blood group A antigen (A-tri-HSA)	Glycoproteins	Saliva	GalNAc(a1-3)[Fuc(a1-2)]Gal(b)-O-APE	Binding	18701592
Clostridium difficile	Unknown	α-Gal on Fab of IgA(κ) MAb	Glycoproteins	Mouse	Gal	Binding	9573079
Clostridium difficile	Unknown	α-Gal on Fab of IgM(λ) MAb	Glycoproteins	Mouse	Gal	Binding	9573079
Streptococcus gordonii	Ca2+-independent lectins	Hs antigen	Glycoproteins		NeuAc(a2-3)Gal(b1-4)Glc-HSA	Binding	9393794
Adeno-associated virus	Unknown	Glycoproteins with α2,3 N-linked sialic acid	Glycoproteins		NeuAc(a2-3)Gal(b1-4)GlcNAc	Binding	16940521