GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule	Ligand Name	Ligand Feature	Target Source	Glycan Sequence ▲	Binding	PubMed ID
Norovirus	Unknown	Blood group H antigen	Disaccharides	Saliva	Fuc(a1-2)Gal	Not Binding	18701592
Escherichia coli	Unknown	unnamed ligand	Glycosphingolipids		Fuc(a1-2)Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	2435422
Actinomyces viscosus	Unknown	unnamed ligand	Glycosphingolipids	Human meconium	Fuc(a1-2)Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer	Not Binding	2358461
Shigella dysenteriae	B subunit	unnamed ligand	Glycosphingolipids	Human meconium	Fuc(a1-2)Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer	Not Binding	3543013
Actinomyces naeslundii	Unknown	unnamed ligand	Glycosphingolipids	Human meconium	Fuc(a1-2)Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer	Not Binding	2358461
Shigella dysenteriae	Shiga toxin	unnamed ligand	Glycosphingolipids		Fuc(a1-2)Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer	Not Binding	2435422
Shigella dysenteriae	Unknown	unnamed ligand	Glycosphingolipids		Fuc(a1-2)Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer	Not Binding	2435422
Helicobacter pylori	35S-labeled or 125I-labeled proteins	Fucosyl Asialo GM1	Oligoglycosylceramides	Mouse small intestine	Fuc(a1-2)Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	9499377
Propionibacterium granulosum	Lectin-like proteins (adhesin)	Fucosyl Asialo GM1	Oligoglycosylceramides	Human skin	Fuc(a1-2)Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	2468365
Lactobacillus johnsonii	Unknown	Fucosyl Asialo GM1	Oligoglycosylceramides	Mouse small intestine	Fuc(a1-2)Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	11087711