GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species ▲	Pathogen Adherence Molecule	Ligand Name	Ligand Feature	Target Source	Glycan Sequence	Binding	PubMed ID
Actinomyces naeslundii	Type 2-fimbriae	β-linked galactosamine	Saccharides	Plaque	GalNAc(b 2:2	Binding	9712794
Actinomyces naeslundii	Type-2 fimbrial lectins	GD1a	Disialoglycosphingolipids		NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Binding	3804448
Actinomyces naeslundii	Type-2 fimbrial lectins	GD1b	Disialoglycosphingolipids		Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Binding	3804448
Actinomyces naeslundii	Type-2 fimbrial lectins	GM1	Monosialoglycosphingolipids		Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Binding	3804448
Actinomyces naeslundii	Type-2 fimbrial lectins	GT1b	Trisialoglycosphingolipids		NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Binding	3804448
Actinomyces naeslundii	Type-2 fimbrial lectins	Gb4 (Globoside; Globotetraose; P antigen)	Oligoglycosylceramides		GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	3804448
Actinomyces naeslundii	Unknown	unnamed ligand	Oligosaccharides		Gal(b1-3)GalNAc	Binding	12628483
Actinomyces naeslundii	Adhesins	PMN (polymorphonuclear leukocytes) surface glycoproteins	Glycoproteins	Human peripheral blood buffy coat cells		Binding	11035744
Actinomyces naeslundii	Adhesins	Asialofetuin	Glycoproteins	HL-60 promyelocytic leukemia cell line		Binding	11035744
Actinomyces naeslundii	Unknown	GD1a	Disialoglycosphingolipids	Human brain	NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Not Binding	2358461