GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule	Ligand Name	Ligand Feature ▲	Target Source	Glycan Sequence	Binding	PubMed ID
Mycoplasma pneumoniae	Unknown	Glycoproteins with terminal NeuAcα3Galβ4GlcNAc-sequences	Glycoproteins		NeuAc(a2-3)Gal(b1-4)GlcNAc	Binding	15973004
Escherichia coli	Type 1-fimbriae	Mannose-derived neoglycoproteins and dendrimers	Glycoproteins		Man	Binding	16564136
Norovirus	Unknown	Blood group B antigen (B-tri-HSA)	Glycoproteins		Gal(a1-3)[Fuc(a1-2)]Gal(b)-O-APE	Binding	18701592
Norovirus	Unknown	Blood group A antigen (A-tri-HSA)	Glycoproteins		GalNAc(a1-3)[Fuc(a1-2)]Gal(b)-O-APE	Binding	18701592
Streptococcus suis	Unknown	Neoglycoproteins (containing Pk Antigen)	Glycoproteins		Gal(a1-4)Gal(b1-4)Glc	Binding	8440715
Parvovirus	Unknown	O-linked alpha 2,3 neuraminic acid on glycophorin A (GPA)	Glycoproteins	Human erythrocytes		Binding	15750863
Streptococcus gordonii	Adhesins	PMN (polymorphonuclear leukocytes) surface glycoproteins in the presence of sialic acid	Glycoproteins	Human peripheral blood buffy coat cells		Binding	11035744
Rubulavirus	Unknown	N-linked sialylated glycoproteins	Glycoproteins	Pig neurons, glial cells		Binding	16459111
Actinomyces naeslundii	Adhesins	PMN (polymorphonuclear leukocytes) surface glycoproteins	Glycoproteins	Human peripheral blood buffy coat cells		Binding	11035744
Actinomyces naeslundii	Adhesins	Asialofetuin	Glycoproteins	HL-60 promyelocytic leukemia cell line		Binding	11035744