Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB) June 1, 2016
Species Pathogen Adherence Molecule Ligand Name Ligand Feature Target Source Glycan Sequence ▼ Binding PubMed ID
S-fimbriae
NeuAcα3Galβ-containing glycoproteins
Glycoproteins
Lumenal surfaces of the vascular endothelium in the neonatal rat brain
NeuAc(a2-3)Gal(b
Binding
SfaS
NeuAcα3Galβ-containing glycoproteins
Glycoproteins
Lumenal surfaces of the vascular endothelium in the neonatal rat brain
NeuAc(a2-3)Gal(b
Binding
Fibrillar hemmagglutinin
N-acetylneuraminyl-a(2-3)-galactopyranosyl sequence
Glycoproteins
Gastric epithelium, Mucus layer of the stomach
NeuAc(a2-3)Gal
Binding
Unknown
Sia2-3Gal-containing receptors
Glycoconjugates
NeuAc(a2-3)Gal
Binding
Unknown
Sialic acid (α2,3)
Saccharides
Most organs including the central nervous system/heart/liver
NeuAc(a2-3)
Binding
VP2 amino acids on puff B
Sialic acid (α2,3)
Saccharides
Central nervous system
NeuAc(a2-3)
Binding
68-kDa proteins
N-Acetylneuraminic acid
Monosaccharides
Bronchial lavages of sheep with pneumonic pasteurelosis
NeuAc
Binding
Viral protein
α-mannose and α-glucose side chains of ConA-binding glycoproteins
Glycoproteins
Feline kidney(CRFK)/Equine fetal kidney(EFK)/Mouse(McCoy)/Rabbit kidney(RK-13)
Man/Glc
Binding
Type 1-fimbriae
Synthetic branched oligosaccharides: Man(a1-3)[Man(a1-6)]Man(a1-6)Man(a1-3)Man
Oligosaccharides
Patient with urinary tract infection
Man(a1-3)[Man(a1-6)]Man(a1-6)[Man(a1-3)]Man
Binding
Type 1-fimbriae
Synthetic branched oligosaccharides: Man(a1-3)[Man(a1-6)]Man(a1-6)[Man(a1-2)]Man(a1-3)Man
Oligosaccharides
Patient with urinary tract infection
Man(a1-3)[Man(a1-6)]Man(a1-6)[Man(a1-2)Man(a1-3)]Man
Binding
Displaying entries 291 - 300 of 1840 in total

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01