PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
Database | Last Updated |
---|---|
Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence ▼ | Binding | PubMed ID |
---|---|---|---|---|---|---|---|
S-fimbriae
|
NeuAcα3Galβ-containing glycoproteins
|
Glycoproteins
|
Lumenal surfaces of the vascular endothelium in the neonatal rat brain
|
NeuAc(a2-3)Gal(b
|
Binding
|
||
SfaS
|
NeuAcα3Galβ-containing glycoproteins
|
Glycoproteins
|
Lumenal surfaces of the vascular endothelium in the neonatal rat brain
|
NeuAc(a2-3)Gal(b
|
Binding
|
||
Fibrillar hemmagglutinin
|
N-acetylneuraminyl-a(2-3)-galactopyranosyl sequence
|
Glycoproteins
|
Gastric epithelium, Mucus layer of the stomach
|
NeuAc(a2-3)Gal
|
Binding
|
||
Unknown
|
Sia2-3Gal-containing receptors
|
Glycoconjugates
|
NeuAc(a2-3)Gal
|
Binding
|
|||
Unknown
|
Sialic acid (α2,3)
|
Saccharides
|
Most organs including the central nervous system/heart/liver
|
NeuAc(a2-3)
|
Binding
|
||
VP2 amino acids on puff B
|
Sialic acid (α2,3)
|
Saccharides
|
Central nervous system
|
NeuAc(a2-3)
|
Binding
|
||
68-kDa proteins
|
N-Acetylneuraminic acid
|
Monosaccharides
|
Bronchial lavages of sheep with pneumonic pasteurelosis
|
NeuAc
|
Binding
|
||
Viral protein
|
α-mannose and α-glucose side chains of ConA-binding glycoproteins
|
Glycoproteins
|
Feline kidney(CRFK)/Equine fetal kidney(EFK)/Mouse(McCoy)/Rabbit kidney(RK-13)
|
Man/Glc
|
Binding
|
||
Type 1-fimbriae
|
Synthetic branched oligosaccharides: Man(a1-3)[Man(a1-6)]Man(a1-6)Man(a1-3)Man
|
Oligosaccharides
|
Patient with urinary tract infection
|
Man(a1-3)[Man(a1-6)]Man(a1-6)[Man(a1-3)]Man
|
Binding
|
||
Type 1-fimbriae
|
Synthetic branched oligosaccharides: Man(a1-3)[Man(a1-6)]Man(a1-6)[Man(a1-2)]Man(a1-3)Man
|
Oligosaccharides
|
Patient with urinary tract infection
|
Man(a1-3)[Man(a1-6)]Man(a1-6)[Man(a1-2)Man(a1-3)]Man
|
Binding
|
GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.
Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01