GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule	Ligand Name	Ligand Feature	Target Source	Glycan Sequence	Binding	PubMed ID ▼
Legionella pneumophila	Adhesins	Asialo-GM2 (Gangliotriosylceramide; GgO3)	Oligoglycosylceramides	Human epithelial cells (respiratory tract)	GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	14687561
Legionella pneumophila	Adhesins	unnamed ligand	Oligosaccharides	Human epithelial cells (respiratory tract)	Gal(b1-4)GlcNAc	Binding	14687561
Legionella pneumophila	Adhesins	GD1a	Disialoglycosphingolipids	Human epithelial cells (respiratory tract)	NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Not Binding	14687561
Legionella pneumophila	Adhesins	GM3(NeuAc)	Monosialoglycosphingolipids	Human epithelial cells (respiratory tract)	NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer	Not Binding	14687561
Legionella pneumophila	Adhesins	GM1	Monosialoglycosphingolipids	Human epithelial cells (respiratory tract)	Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Not Binding	14687561
Legionella pneumophila	Adhesins	GM2(NeuAc)	Monosialoglycosphingolipids	Human epithelial cells (respiratory tract)	GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Not Binding	14687561
Legionella pneumophila	Adhesins	Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1)	Oligoglycosylceramides	Human epithelial cells (respiratory tract)	Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	14687561
Bordetella pertussis	Pertussis toxin	Fetuin	Glycoproteins	Bovine		Binding	14532091
Bordetella pertussis	Unknown	Fetuin	Glycoproteins	Bovine		Binding	14532091
Reovirus	sigma 1 proteins	Sialic acid	Monosaccharides	Murine intestine, Murine spleen, Murine liver, Murine brain, Human cholangiocarcinoma cells		Binding	12813018