GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species ▲	Pathogen Adherence Molecule	Ligand Name	Ligand Feature	Target Source	Glycan Sequence	Binding	PubMed ID
Clostridium tetani	Unknown	GD1b	Disialoglycosphingolipids		Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Binding	7527546
Clostridium tetani	Tetanus neurotoxin	GM2(NeuAc)	Monosialoglycosphingolipids		GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Binding	15973004
Clostridium tetani	Unknown	GM2(NeuAc)	Monosialoglycosphingolipids		GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Binding	15973004
Clostridium tetani	Tetanus neurotoxin	GT1b	Trisialoglycosphingolipids		NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Binding	12628483
Clostridium tetani	Tetanus toxin	GT1b	Trisialoglycosphingolipids		NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Binding	7527546
Clostridium tetani	Unknown	GT1b	Trisialoglycosphingolipids		NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Binding	12628483
Clostridium tetani	Unknown	GT1b	Trisialoglycosphingolipids		NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Binding	7527546
Clostridium tetani	Tetanus toxin (Hc fragment)	GT1b analog	Trisialoglycosphingolipids	Synapse		Binding	18809496
Clostridium tetani	Unknown	GT1b analog	Trisialoglycosphingolipids	Synapse		Binding	18809496
Clostridium tetani	Tetanus neurotoxin	Polysialogangliosides and other acidic lipids	Glycolipids	Presynaptic membrane of neuromuscular junction		Binding	7527117