GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule	Ligand Name	Ligand Feature	Target Source	Glycan Sequence ▲	Binding	PubMed ID
Propionibacterium granulosum	Unknown	Galactosylceramide (Galactocerebroside)	Monoglycosylceramides		Gal(b1-1)Cer	Not Binding	2435422
Actinobacillus pleuropneumoniae	LPS	Galactosylceramide (hydroxylated/nonhydroxylated fatty acids)	Monoglycosylceramides		Gal(b1-1)Cer	Binding	10496867
Human immunodeficiency virus	Unknown	Galactosylceramide (or derivative)	Monoglycosylceramides	Human colon epithelial HT29 cells	Gal(b1-1)Cer	Binding	1378511
Actinomyces naeslundii	Type-2 fimbrial lectins (130-kDa glycoprotein)	unnamed ligand	Oligosaccharides	Polymorphonuclear leukocytes (PMNs)	Gal(b1-3)GalNAc	Binding	7790078
Fusobacterium nucleatum	Lectin-like proteins (adhesin)	unnamed ligand	Oligosaccharides		Gal(b1-3)GalNAc	Binding	1894623
Actinomyces naeslundii	Unknown	unnamed ligand	Oligosaccharides		Gal(b1-3)GalNAc	Binding	12628483
Actinomyces viscosus	Unknown	SSEA-3 (GSL) (Galactosyl globoside; Gb5)	Oligoglycosylceramides	Vero cells	Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer	Not Binding	2358461
Shigella dysenteriae	B subunit	SSEA-3 (GSL) (Galactosyl globoside; Gb5)	Oligoglycosylceramides	Human kidney	Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer	Not Binding	3543013
Actinomyces naeslundii	Unknown	SSEA-3 (GSL) (Galactosyl globoside; Gb5)	Oligoglycosylceramides	Vero cells	Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	2358461
Shigella dysenteriae	Shiga toxin	SSEA-3 (GSL) (Galactosyl globoside; Gb5)	Oligoglycosylceramides		Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer	Not Binding	2435422