Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB) June 1, 2016
Species Pathogen Adherence Molecule Ligand Name Ligand Feature Target Source ▲ Glycan Sequence Binding PubMed ID
Adhesins
GM1
Monosialoglycosphingolipids
Human epithelial cells (respiratory tract)
Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer
Not Binding
Adhesins
GM2(NeuAc)
Monosialoglycosphingolipids
Human epithelial cells (respiratory tract)
GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer
Not Binding
Adhesins
Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1)
Oligoglycosylceramides
Human epithelial cells (respiratory tract)
Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer
Binding
HMW1
unknown carbohydrate ligand
Saccharides
Human epithelial cells (respiratory tract)
Binding
HMW2
unknown carbohydrate ligand
Saccharides
Human epithelial cells (respiratory tract)
Binding
PrsG (class III)
Gb4 (Globoside; Globotetraose; P antigen)
Oligoglycosylceramides
Human erythrocytes
GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer
Binding
PapG (class I)
Gb4 (Globoside; Globotetraose; P antigen)
Oligoglycosylceramides
Human erythrocytes
GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer
Binding
P-fimbriae
Gb4 (Globoside; Globotetraose; P antigen)
Oligoglycosylceramides
Human erythrocytes
GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer
Binding
PapG (class II)
Gb4 (Globoside; Globotetraose; P antigen)
Oligoglycosylceramides
Human erythrocytes
GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer
Binding
Unknown
nLc4Cer (Neolactotetraosylceramide; Paragloboside)
Oligoglycosylceramides
Human erythrocytes
Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer
Binding
Displaying entries 321 - 330 of 1840 in total

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01