GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule	Ligand Name	Ligand Feature ▲	Target Source	Glycan Sequence	Binding	PubMed ID
Escherichia coli	Unknown	Gb2 (Galabiosylceramide)	Diosylceramides		Gal(a1-4)Gal(b1-1)Cer	Binding	2435422
Shigella dysenteriae	Unknown	Gb2 (Galabiosylceramide)	Diosylceramides		Gal(a1-4)Gal(b1-1)Cer	Binding	2435422
Shigella dysenteriae	Unknown	Gb2 (Galabiosylceramide)	Diosylceramides		Gal(a1-4)Gal(b1-1)Cer	Binding	12628483
Bordetella pertussis	CRD (carbohydrate recognition domain) of Fha (Filamentous Hemagglutinin)	Lactosylceramide (Lactocerebroside)	Diosylceramides	Respiratory ciliated cells, Alveolar macrophages	Gal(b1-4)Glc(b1-1)Cer	Binding	8514379
Escherichia coli	S-fimbriae (SfaA)	Lactosylceramide (Lactocerebroside)	Diosylceramides	Brain endothelial cells	Gal(b1-4)Glc(b1-1)Cer	Binding	8098039
Pseudomonas aeruginosa	Type 4-pili	Lactosylceramide (Lactocerebroside)	Diosylceramides	Epithelial cells	Gal(b1-4)Glc(b1-1)Cer	Binding	9224879
Bordetella pertussis	Pertussis toxin	Lactosylceramide (Lactocerebroside)	Diosylceramides	Human cilia of the respiratory epithelium	Gal(b1-4)Glc(b1-1)Cer	Binding	1729677
Saccharomyces cerevisiae	Unknown	Lactosylceramide (Lactocerebroside)	Diosylceramides	Human lung, Human polymorphonuclear leukocytes, Human glioma brain cells	Gal(b1-4)Glc(b1-1)Cer	Binding	2194958
Propionibacterium granulosum	Unknown	Lactosylceramide (Lactocerebroside)	Diosylceramides	Whole dog small intestine	Gal(b1-4)Glc(b1-1)Cer	Binding	2452754
Sporothrix schenckii	Unknown	Lactosylceramide (Lactocerebroside)	Diosylceramides	Human lung, Human polymorphonuclear leukocytes	Gal(b1-4)Glc(b1-1)Cer	Binding	2194958