Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB) June 1, 2016
Species Pathogen Adherence Molecule ▲ Ligand Name Ligand Feature Target Source Glycan Sequence Binding PubMed ID
17-kDa HBP (Heparin-binding protein)
von Willebrand factor (VWF)
Glycoproteins
Binding
17-kDa HBP (Heparin-binding protein)
Thrombospondin (TSP)
Glycoproteins
Binding
17-kDa HBP (Heparin-binding protein)
Thrombospondin (TSP)
Glycoproteins
Binding
18-kDa fimbrial adhesin
Galactose derivatives
Saccharides
HEp-2 cells
Gal
Binding
18-kDa proteins
Asialo-GM2 (Gangliotriosylceramide; GgO3)
Oligoglycosylceramides
GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer
Binding
18-kDa proteins
unnamed ligand
Oligosaccharides
Gal(a1-4)Gal
Binding
18-kDa proteins
unnamed ligand
Oligosaccharides
Mucos membranes of the genitourinary tract/rectum/oropharynx/conjunctiva
Gal(b1-4)GlcNAc(b1-4)Gal(b1-4)Glc
Binding
20K-fimbriae
GlcNAc sequence
Saccharides
Human colon carcinoma Caco-2 cell line
GlcNAc
Binding
33-kDa proteins
factor H (fH)
Glycoproteins
Binding
35S-labeled or 125I-labeled proteins
isoGb3 (Isoglobotriaosylceramide; iGb3)
Oligoglycosylceramides
Dog small intestine
Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer
Binding
Displaying entries 31 - 40 of 1840 in total

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01