GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule	Ligand Name	Ligand Feature	Target Source	Glycan Sequence	Binding	PubMed ID ▼
Influenza virus	Hemagglutinin H1(1934)	Human and avian receptors containing sialylated glycoconjugates	Glycoconjugates	Airways		Binding	18809496
Paramyxovirus	Hemagglutinin H1(1934)	Human and avian receptors containing sialylated glycoconjugates	Glycoconjugates	Airways		Binding	18809496
Pseudomonas aeruginosa	PA-IIL	Lewis a (Lea) (GSL)	Glycosphingolipids	Airways	Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer	Binding	18809496
Norovirus	Capsid proteins	Blood group B antigen	Oligosaccharides		Gal(a1-3)[Fuc(a1-2)]Gal	Binding	18809496
Norovirus	Capsid proteins	Blood group A antigen	Oligosaccharides		GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-3)GlcNAc	Binding	18809496
Staphylococcus aureus	SSL5	Sialyl Lewis x (SLex) antigen	Oligosaccharides	(broad range)	NeuAc(a2-3)Gal(b1-4)	Binding	18809496
Staphylococcus aureus	SSL11	Sialyl Lewis x (SLex) antigen	Oligosaccharides	(broad range)	NeuAc(a2-3)Gal(b1-4)	Binding	18809496
Escherichia coli	Shiga-like toxin (Stx1)	Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH)	Oligoglycosylceramides	GI/kidney	Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	18809496
Escherichia coli	Unknown	Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH)	Oligoglycosylceramides	GI/kidney	Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	18809496
Norovirus	Capsid proteins	Blood group H1 antigen	Oligosaccharides		Fuc(a1-2)Gal(b1-3)GlcNAc	Binding	18809496