GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule	Ligand Name	Ligand Feature	Target Source ▲	Glycan Sequence	Binding	PubMed ID
Escherichia coli	S-fimbriae (SfaA)	Galactosyl sulfatide	Sulfoglycosphingolipids	Brain endothelial cells	Gal(3SO4)(b1-1)Cer	Binding	8098039
Escherichia coli	S-fimbriae (SfaA)	Lactosylceramide (Lactocerebroside)	Diosylceramides	Brain endothelial cells	Gal(b1-4)Glc(b1-1)Cer	Binding	8098039
Clostridium tetani	Tetanus toxin	GD1b	Disialoglycosphingolipids	Brain membrane	Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Binding	6257717
Clostridium tetani	Unknown	GD1b	Disialoglycosphingolipids	Brain membrane	Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Binding	6257717
Clostridium tetani	Tetanus toxin	GT1b	Trisialoglycosphingolipids	Brain membrane	NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Binding	6257717
Clostridium tetani	Unknown	GT1b	Trisialoglycosphingolipids	Brain membrane	NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Binding	6257717
Pasteurella haemolytica	68-kDa proteins	N-Acetylglucosamine	Monosaccharides	Bronchial lavages of sheep with pneumonic pasteurelosis	GlcNAc	Binding	10570221
Pasteurella haemolytica	68-kDa proteins	N-Acetylneuraminic acid	Monosaccharides	Bronchial lavages of sheep with pneumonic pasteurelosis	NeuAc	Binding	10570221
Actinomyces naeslundii	Type 2-fimbriae	β-linked galactosamine	Saccharides	Buccae	GalNAc(b 2:2	Binding	9712794
Actinomyces odontolyticus	Type 2-fimbriae	β-linked galactosamine	Saccharides	Buccae	GalNAc(b 2:2	Binding	9712794