PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
Database | Last Updated |
---|---|
Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
---|---|---|---|---|---|---|---|
Unknown
|
Sulfatide (CSE)
|
Sulfoglycosphingolipids
|
Intestinal tract
|
HSO3(-3)Gal(b1-1)Cer
|
Binding
|
||
Botulinum neurotoxin (type C)
|
GT1b
|
Trisialoglycosphingolipids
|
Presynaptic neuronal cells
|
NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
||
Tetanus toxin
|
GT1b
|
Trisialoglycosphingolipids
|
Brain membrane
|
NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
||
BoNT/C (located within amino acid residues 1122-1290)
|
GT1b
|
Trisialoglycosphingolipids
|
Presynaptic neuronal cells
|
NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
||
Hemagglutinin (HA)
|
GT1b
|
Trisialoglycosphingolipids
|
Various human tissues (leukocytes/erythrocytes/small intestine/stomach/meconium/colon/pancreas)
|
NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
||
Unknown
|
GT1b
|
Trisialoglycosphingolipids
|
Brain membrane
|
NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
||
F1C
|
Lactosylceramide (t18:0-h16:0-h24:0)
|
Diosylceramides
|
Rabbit small intestine
|
Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
||
PapG
|
alpha-D-galactopyranosyl-(1-4)-beta-D-galactopyranose
|
Disaccharides
|
Uroepithelial cells
|
Gal(a1-4)Gal
|
Binding
|
||
K1
|
unnamed ligand
|
Disaccharides
|
Endothelial cells
|
GlcNAc(b1-4)GlcNAc
|
Binding
|
||
Progenitor toxin (type A)
|
Lactose
|
Disaccharides
|
Intestine-407 cells
|
Gal(b1-4)Glc
|
Binding
|
GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.
Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01