GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule	Ligand Name	Ligand Feature ▲	Target Source	Glycan Sequence	Binding	PubMed ID
Candida albicans	Unknown	Lactosylceramide (Lactocerebroside)	Diosylceramides	Human lung, Human polymorphonuclear leukocytes, Human glioma brain cells	Gal(b1-4)Glc(b1-1)Cer	Binding	2194958
Bordetella pertussis	FHA (1141-1279)	Lactosylceramide (Lactocerebroside)	Diosylceramides	Ciliated epithelium of the respiratory tract	Gal(b1-4)Glc(b1-1)Cer	Binding	11348687
Histoplasma capsulatum	Adhesins	Lactosylceramide (Lactocerebroside)	Diosylceramides	Phagocytes	Gal(b1-4)Glc(b1-1)Cer	Binding	19547878
Bordetella pertussis	PT (subunit S2 of B oligomer)	Lactosylceramide (Lactocerebroside)	Diosylceramides	Human cilia of the respiratory epithelium	Gal(b1-4)Glc(b1-1)Cer	Binding	1729677
Neisseria gonorrhoeae	Lectin-like proteins (adhesin)	Lactosylceramide (Lactocerebroside)	Diosylceramides	Gonorrhoeae patients	Gal(b1-4)Glc(b1-1)Cer	Binding	2468365
Actinomyces viscosus	Unknown	Lactosylceramide (Lactocerebroside)	Diosylceramides	Dog small intestine	Gal(b1-4)Glc(b1-1)Cer	Binding	2358461
Actinomyces viscosus	Unknown	Lactosylceramide (Lactocerebroside)	Diosylceramides	Human erythrocytes	Gal(b1-4)Glc(b1-1)Cer	Not Binding	2358461
Mycoplasma pneumoniae	Unknown	Lactosylceramide (Lactocerebroside)	Diosylceramides	Human colon adenocarcinoma cells (WiDr )	Gal(b1-4)Glc(b1-1)Cer	Binding	2470753
Lactobacillus johnsonii	Unknown	Lactosylceramide (Lactocerebroside)	Diosylceramides	Dog small intestine	Gal(b1-4)Glc(b1-1)Cer	Binding	11087711
Histoplasma capsulatum	Unknown	Lactosylceramide (Lactocerebroside)	Diosylceramides	Human lung, Human polymorphonuclear leukocytes	Gal(b1-4)Glc(b1-1)Cer	Binding	2194958