GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule ▼	Ligand Name	Ligand Feature	Target Source	Glycan Sequence	Binding	PubMed ID
Norovirus	Unknown	Sialyl Lewis x (SLex-HSA)	Glycoproteins	Human serum albumin	NeuAc(a2-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)Glc(c)-APD	Binding	19054801
Influenza virus	Unknown	GM3(NeuAc)	Monosialoglycosphingolipids	Granulocytes	NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer	Binding	8823909
Influenza virus	Unknown	Sialyl-3-Paragloboside (S-3-PG; α2,3-sialylparagloboside)	Monosialoglycosphingolipids	Granulocytes	NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer	Binding	8823909
Sendai virus	Unknown	Sialyl-3-Paragloboside (S-3-PG; α2,3-sialylparagloboside)	Monosialoglycosphingolipids	Granulocytes	NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer	Binding	8823909
Actinomyces naeslundii	Unknown	GM1	Monosialoglycosphingolipids	Human brain	Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Binding	2358461
Helicobacter pylori	Unknown	unnamed ligand	Oligosaccharides	Stomach	NeuAc(a2-3)Gal(b1-4)GlcNAc	Binding	16564136
Polyoma virus	Unknown	Sialylated oligosaccharides	Oligosaccharides	Erythrocytes	NeuAc(a2-3)Gal(b1-3)GalNAc	Binding	6316632
Polyoma virus	Unknown	unnamed ligand	Oligosaccharides	Murine small plaque	NeuAc(a2-3)Gal(b1-3)[NeuAc(a2-6)]GalNAc	Binding	8574698
Reovirus	Unknown	Sialic acid (α2,6)	Saccharides	Most organs including the central nervous system/heart/liver	NeuAc(a2-6)	Binding	18216114
Mycoplasma pneumoniae	Unknown	Sulfo-lactosylceramide (SM3)	Sulfoglycosphingolipids	Human colon adenocarcinoma cells (WiDr )	HSO3(-3)Gal(b1-4)Glc(b1-1)Cer	Binding	2470753