GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule	Ligand Name	Ligand Feature	Target Source ▼	Glycan Sequence	Binding	PubMed ID
Escherichia coli	F17	N-Acetylglucosamine	Monosaccharides	Urine (microvilli of the intestinal epithelium of ruminants)	GlcNAc	Binding	16564136
Escherichia coli	F1C	unnamed ligand	Saccharides	Urine	GalNAc(b1-4)Gal(b	Binding	16564136
Escherichia coli	P-fimbriae	Gb2 (Galabiosylceramide)	Diosylceramides	Urine	Gal(a1-4)Gal(b1-1)Cer	Binding	16564136
Escherichia coli	Type 1-fimbriae	unnamed ligand	Oligosaccharides	Urine	Man(a1-3)Man(a1-6)Man	Binding	16564136
Shigella dysenteriae	Stx	Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH)	Oligoglycosylceramides	Ubiquitously expressed in most tissues (e.g. human erythrocytes/endothelium/kidney/platelet)	Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	9712788
Streptococcus pneumoniae	Adhesins	N-Acetylgalactosamine	Monosaccharides	Type-II lung cells, Vascular endothelial cells	GalNAc	Binding	7752878
Streptococcus pneumoniae	Adhesins	D-Mannose	Monosaccharides	Type-II lung cells, Vascular endothelial cells	Man	Binding	7752878
Streptococcus pneumoniae	Adhesins	Asialo-GM2 (Gangliotriosylceramide; GgO3)	Oligoglycosylceramides	Type-II lung cells, Vascular endothelial cells	GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	7752878
Streptococcus pneumoniae	Adhesins	Gb4 (Globoside; Globotetraose; P antigen)	Oligoglycosylceramides	Type-II lung cells, Vascular endothelial cells	GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	7752878
Streptococcus pneumoniae	Adhesins	Gb5 (Forssman glycolipid)	Oligoglycosylceramides	Type-II lung cells, Vascular endothelial cells	GalNAc(a1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	7752878