GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule	Ligand Name	Ligand Feature	Target Source	Glycan Sequence	Binding	PubMed ID ▼
Reovirus	Unknown	Sialic acid (α2,6)	Saccharides	Most organs including the central nervous system/heart/liver	NeuAc(a2-6)	Binding	18216114
Reovirus	Unknown	Sialic acid (α2,3)	Saccharides	Most organs including the central nervous system/heart/liver	NeuAc(a2-3)	Binding	18216114
Reovirus	Unknown	Junctional adhesion molecule A (JAM-A)	Glycoproteins	Most organs including the central nervous system/heart/liver		Binding	18216114
Paracoccidioides brasiliensis	Adhesins	Fibronectin	Glycoproteins	Human type II alveolar cells (A549)		Binding	18083324
Paracoccidioides brasiliensis	Adhesins	Fibrinogen	Glycoproteins	Human type II alveolar cells (A549)		Binding	18083324
Neisseria meningitidis	OpcA	Sialic acid-containing polysaccharides	Polysaccharides	Epithelial cells		Binding	18076035
Staphylococcus aureus	Unknown	MUC16 mucin	Glycoproteins	Human corneal-limbal epithelial(HCLE) cells		Binding	17898272
Bordetella pertussis	Iron-induced surface-exposed proteins	Mucin	Glycoproteins	Respiratory epithelial cells (A549)		Binding	17727651
Bordetella pertussis	Iron-induced surface-exposed proteins	Sialic acid	Monosaccharides	Respiratory epithelial cells (A549)		Binding	17727651
Lassa virus	Glycoprotein (GP)	O-mannosyl glycans on alpha-dystroglycan (DG)	O-glycans	Fibroblasts, Epithelial cells, Endothelial cells, Hepatocytes		Binding	17360738