GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule	Ligand Name	Ligand Feature	Target Source ▲	Glycan Sequence	Binding	PubMed ID
Streptococcus pneumoniae	Unknown	Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1)	Oligoglycosylceramides	Chinchilla tracheal epithelium	Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	10090858
Streptococcus pneumoniae	Unknown	unnamed ligand	Oligosaccharides	Chinchilla tubotympanum	Gal(b1-4)GlcNAc(b1-3)Gal(b	Binding	1298868
Bordetella pertussis	FHA (1141-1279)	Lactosylceramide (Lactocerebroside)	Diosylceramides	Ciliated epithelium of the respiratory tract	Gal(b1-4)Glc(b1-1)Cer	Binding	11348687
Shigella dysenteriae	Adhesins	Colonic mucin	Glycoproteins	Colon		Binding	11381327
Escherichia coli	PrsG (class III)	Glucosylceramide	Monoglycosylceramides	Colonic adenocarcinoma	Glc(b1-1)Cer	Not Binding	9673272
Escherichia coli	PapG (class I)	Glucosylceramide	Monoglycosylceramides	Colonic adenocarcinoma	Glc(b1-1)Cer	Not Binding	9673272
Escherichia coli	P-fimbriae	Glucosylceramide	Monoglycosylceramides	Colonic adenocarcinoma	Glc(b1-1)Cer	Not Binding	9673272
Escherichia coli	PapG (class II)	Glucosylceramide	Monoglycosylceramides	Colonic adenocarcinoma	Glc(b1-1)Cer	Not Binding	9673272
Pseudomonas aeruginosa	Unknown	Asialo-GM2 (Gangliotriosylceramide; GgO3)	Oligoglycosylceramides	Cystic fibrosis patients	GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	15973004
Pseudomonas aeruginosa	Unknown	Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1)	Oligoglycosylceramides	Cystic fibrosis patients	Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	15973004