PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
Database | Last Updated |
---|---|
Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source ▼ | Glycan Sequence | Binding | PubMed ID |
---|---|---|---|---|---|---|---|
FimA (Lral family); localized to the tip of peritrichous surface fimbria
|
Salivary glycoprotein
|
Glycoproteins
|
Tooth surface
|
Binding
|
|||
Type 2-fimbriae
|
β-linked galactosamine
|
Saccharides
|
Tongue
|
GalNAc(b
|
Not Binding
|
||
Unknown
|
unknown carbohydrate ligand
|
Saccharides
|
Tongue
|
Binding
|
|||
F1C
|
Gb2 (Galabiosylceramide)
|
Diosylceramides
|
Synthetic
|
Gal(a1-4)Gal(b1-1)Cer
|
Not Binding
|
||
Tetanus toxin (Hc fragment)
|
GT1b analog
|
Trisialoglycosphingolipids
|
Synapse
|
Binding
|
|||
Unknown
|
GT1b analog
|
Trisialoglycosphingolipids
|
Synapse
|
Binding
|
|||
Adhesins
|
MUC1 mucin
|
Glycoproteins
|
Surface of chinese hamster ovary (CHO) cells
|
Binding
|
|||
Unknown
|
unnamed ligand
|
Oligosaccharides
|
Stomach
|
NeuAc(a2-3)Gal(b1-4)GlcNAc
|
Binding
|
||
Lectin-like proteins (adhesin)
|
Galactosylceramide (Galactocerebroside)
|
Monoglycosylceramides
|
Sputa of cystic fibrosis patients
|
Gal(b1-1)Cer
|
Binding
|
||
Lectin-like proteins (adhesin)
|
Asialo-GM2 (Gangliotriosylceramide; GgO3)
|
Oligoglycosylceramides
|
Sputa of cystic fibrosis patients
|
GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.
Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01