GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule	Ligand Name	Ligand Feature	Target Source	Glycan Sequence	Binding	PubMed ID
Hantaan virus	DBA (Dolichos biflorus agglutinin)	N-Acetylgalactosamine	Monosaccharides	Vero E6/P388D1 cells	GalNAc	Binding	10542025
Actinomyces naeslundii	Adhesins	N-Acetylgalactosamine	Monosaccharides	HL-60 promyelocytic leukemia cell line, Leukosialin (CD43)	GalNAc	Binding	11035744
Actinomyces naeslundii	Adhesins	Galactose	Monosaccharides	HL-60 promyelocytic leukemia cell line, Leukosialin (CD43)	Gal	Binding	11035744
Escherichia coli	F17	N-Acetylglucosamine	Monosaccharides	Urine (microvilli of the intestinal epithelium of ruminants)	GlcNAc	Binding	16564136
Cryptococcus neoformans	Adhesins	N-Acetylglucosamine	Monosaccharides	Human lung epithelial cell line (A549)	GlcNAc	Binding	9453390
Cryptococcus neoformans	Adhesins	N-Acetylgalactosamine	Monosaccharides	Human lung epithelial cell line (A549)	GalNAc	Binding	9453390
Streptococcus pneumoniae	Adhesins	N-Acetylgalactosamine	Monosaccharides	Type-II lung cells, Vascular endothelial cells	GalNAc	Binding	7752878
Streptococcus pneumoniae	Adhesins	D-Mannose	Monosaccharides	Type-II lung cells, Vascular endothelial cells	Man	Binding	7752878
Streptococcus pneumoniae	Adhesins	D-Galactose	Monosaccharides	Vascular endothelial cells (only)	Gal	Binding	7752878
Escherichia coli	Type 1-pili	D-Mannose	Monosaccharides	Bladder epithelium	Man	Binding	12010488