PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
Database | Last Updated |
---|---|
Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID ▼ |
---|---|---|---|---|---|---|---|
Glycoprotein (GP)
|
O-mannosyl glycans on alpha-dystroglycan (DG)
|
O-glycans
|
Fibroblasts, Epithelial cells, Endothelial cells, Hepatocytes
|
Binding
|
|||
Glycoprotein (GP)
|
O-mannosyl glycans on alpha-dystroglycan (DG)
|
O-glycans
|
Binding
|
||||
VP8 (spike protein)
|
Sialic acid(2-O-methyl-α-Neu5Gc (Neu5Gc2Me))
|
Monosaccharides
|
Binding
|
||||
VP8 (galectin)
|
Sialic acid(2-O-methyl-α-Neu5Ac (Neu5Ac2Me))
|
Monosaccharides
|
Binding
|
||||
VP8 (spike protein)
|
Sialic acid
|
Monosaccharides
|
Binding
|
||||
HN(hemagglutinin-neuraminidase) glycoproteins
|
Sialic acid
|
Monosaccharides
|
Binding
|
||||
Botulinum neurotoxin (16S)
|
Lactose
|
Disaccharides
|
Intestinal epithelial cells (T84)
|
Gal(b1-4)Glc
|
Binding
|
||
HA
|
Lactose
|
Disaccharides
|
Intestinal epithelial cells (T84)
|
Gal(b1-4)Glc
|
Binding
|
||
Botulinum neurotoxin (16S)
|
N-Acetylgalactosamine
|
Monosaccharides
|
Intestinal epithelial cells (T84)
|
GalNAc
|
Binding
|
||
Botulinum neurotoxin (16S)
|
Galactose
|
Monosaccharides
|
Intestinal epithelial cells (T84)
|
Gal
|
Binding
|
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Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01