Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Database | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source ▲ | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
|
CbpA; SpsA; PbcA; PspC (CBPs)
|
nLc4Cer (Neolactotetraosylceramide; Paragloboside)
|
Oligoglycosylceramides
|
Cytokine activated epithelial and endothelial cells
|
Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
||
|
CbpA; SpsA; PbcA; PspC (CBPs)
|
Sialic acid
|
Monosaccharides
|
Cytokine activated epithelial and endothelial cells
|
Binding
|
|||
|
CBPs (choline-binding proteins)
|
nLc4Cer (Neolactotetraosylceramide; Paragloboside)
|
Oligoglycosylceramides
|
Cytokine-activated cells
|
Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
||
|
CBPs (choline-binding proteins)
|
Sialic acid
|
Monosaccharides
|
Cytokine-activated cells
|
Binding
|
|||
|
Unknown
|
Salivary glycoprotein (gp340)
|
Glycoproteins
|
Dental plaque (caries-associated)
|
Binding
|
|||
|
PclA (pneumococcal collagen-like protein A)
|
unknown carbohydrate ligand
|
Saccharides
|
Detroit 562/A549 cell lines
|
Binding
|
|||
|
F1C
|
Gb5 (Forssman glycolipid)
|
Oligoglycosylceramides
|
Dog intestine
|
GalNAc(a1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer
|
Not Binding
|
||
|
F1C
|
Lewis x (Lex) (GSL)
|
Oligoglycosylceramides
|
Dog intestine
|
Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer
|
Not Binding
|
||
|
Neutrophil-activating proteins (150-kDa)
|
Lactosylceramide (Lactocerebroside)
|
Diosylceramides
|
Dog intestine
|
Gal(b1-4)Glc(b1-1)Cer
|
Not Binding
|
||
|
35S-labeled or 125I-labeled proteins
|
isoGb3 (Isoglobotriaosylceramide; iGb3)
|
Oligoglycosylceramides
|
Dog small intestine
|
Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
Displaying entries 81 - 90 of 1840 in total
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International Collaboration
GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.
Acknowledgements
Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01
