GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule	Ligand Name	Ligand Feature	Target Source ▼	Glycan Sequence	Binding	PubMed ID
Burkholderia cepacia	Lectin-like proteins (adhesin)	Gb2 (Galabiosylceramide)	Diosylceramides	Sputa of cystic fibrosis patients	Gal(a1-4)Gal(b1-1)Cer	Binding	8606110
Burkholderia cepacia	Lectin-like proteins (adhesin)	Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1)	Oligoglycosylceramides	Sputa of cystic fibrosis patients	Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	8606110
Burkholderia cepacia	Lectin-like proteins (adhesin)	Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH)	Oligoglycosylceramides	Sputa of cystic fibrosis patients	Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	8606110
Escherichia coli	F1C	Galactosylceramide (d18:1-h18:0-h24:0)	Monoglycosylceramides	Sigma	Gal(b1-1)Cer	Not Binding	11877427
Streptococcus pneumoniae	CTB-PsaA pentamers	GM1	Monosialoglycosphingolipids	Serum, Saliva, Nasal/bronchial wash samples	Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer	Binding	15358234
Neisseria meningitidis	PorA	C4b-binding protein (C4bp)	Glycoproteins	Serum		Binding	15879129
Escherichia coli	AC/I-fimbriae (S-fimbrial family)	unknown carbohydrate ligand	Saccharides	Septicemic avian epithelial cells		Binding	10992500
Norovirus	Unknown	Blood group H antigen	Disaccharides	Saliva	Fuc(a1-2)Gal	Binding	18701592
Norovirus	Unknown	Blood group A antigen (A-tri-HSA)	Glycoproteins	Saliva	GalNAc(a1-3)[Fuc(a1-2)]Gal(b)-O-APE	Binding	18701592
Streptococcus mutans	P1 (Antigen I/II)	Salivary glycoprotein	Glycoproteins	Saliva		Binding	12640357