Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Database | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID ▼ |
|---|---|---|---|---|---|---|---|
|
MuV-HN
|
Glycans containing α2,6-linked sialic acid
|
Oligosaccharides
|
NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-3)[NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)GlcNAc
|
Not Binding
|
|||
|
MuV-HN
|
Glycans containing α2,3-linked sialic acid
|
Oligosaccharides
|
NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-2)[NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-4]Man(a1-3)[NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)GlcNAc
|
Binding
|
|||
|
MuV-HN
|
Glycans containing α2,3-linked sialic acid
|
Oligosaccharides
|
NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-2)[NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-4)]Man(a1-3)[NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-2)[NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-6)]Man(a1-6)]Man(b1-4)GlcNAc(b1-4)GlcNAc
|
Not Binding
|
|||
|
MuV-HN
|
Glycans containing α2,6-linked sialic acid
|
Oligosaccharides
|
NeuAc(a2-6)Gal(b1-4)GlcNAc
|
Not Binding
|
|||
|
MuV-HN
|
Glycans containing α2,3-linked sialic acid
|
Oligosaccharides
|
NeuAc(a2-3)Gal(b1-4)GlcNAc
|
Binding
|
|||
|
MuV-HN
|
Glycans containing α2,6-linked sialic acid
|
Oligosaccharides
|
NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-2)[NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-4)]Man(a1-3)[NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)GlcNAc
|
Not Binding
|
|||
|
Lectin-like component
|
Galactosylated surface molecules (mainly β-anomer)
|
Glycoconjugates
|
Murine macrophages
|
Binding
|
|||
|
Adhesins
|
Lactosylceramide (Lactocerebroside)
|
Diosylceramides
|
Phagocytes
|
Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
||
|
Lectin-like component
|
unknown carbohydrate ligand
|
Saccharides
|
Human erythrocytes
|
Binding
|
|||
|
FcsSBP (fucose solute-binding protein)
|
Blood group B antigen
|
Oligosaccharides
|
Gal(a1-3)[Fuc(a1-2)]Gal
|
Binding
|
Displaying entries 1 - 10 of 1840 in total
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International Collaboration
GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.
Acknowledgements
Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01
