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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species ▲ | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Clostridium botulinum | Botulinum neurotoxin (16S) | Fucose | Monosaccharides | Intestinal epithelial cells (T84) | Fuc | Not Binding | 17156748 |
| Clostridium botulinum | HA | Fucose | Monosaccharides | Intestinal epithelial cells (T84) | Fuc | Not Binding | 17156748 |
| Clostridium difficile | Toxin A | α-Gal on Fab of IgA(κ) MAb | Glycoproteins | Mouse | Gal | Binding | 9573079 |
| Clostridium difficile | Toxin A | α-Gal on Fab of IgM(λ) MAb | Glycoproteins | Mouse | Gal | Binding | 9573079 |
| Clostridium difficile | Unknown | α-Gal on Fab of IgA(κ) MAb | Glycoproteins | Mouse | Gal | Binding | 9573079 |
| Clostridium difficile | Unknown | α-Gal on Fab of IgM(λ) MAb | Glycoproteins | Mouse | Gal | Binding | 9573079 |
| Clostridium difficile | Toxin A | unnamed ligand | Oligosaccharides | Human colonic cells | Gal(a1-3)Gal(b1-4)GlcNAc | Binding | 12507507 |
| Clostridium difficile | C-terminal domain of toxin A molecules | unnamed ligand | Oligosaccharides | Human colonic cells | Gal(a1-3)Gal(b1-4)GlcNAc | Binding | 12507507 |
| Clostridium difficile | Toxin A | β-Gal on Fab of IgG3(λ) MAb | Glycoproteins | Mouse | Gal | Binding | 9573079 |
| Clostridium difficile | Unknown | β-Gal on Fab of IgG3(λ) MAb | Glycoproteins | Mouse | Gal | Binding | 9573079 |
| Clostridium difficile | Toxin A | unnamed ligand | Oligosaccharides | Human colonic cells | GalNAc(b1-3)Gal(b1-4)GlcNAc | Binding | 12507507 |
| Clostridium difficile | C-terminal domain of toxin A molecules | unnamed ligand | Oligosaccharides | Human colonic cells | GalNAc(b1-3)Gal(b1-4)GlcNAc | Binding | 12507507 |
| Clostridium perfringens | Delta toxin (type C) | GM2(NeuAc) | Monosialoglycosphingolipids | GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 6260669 | |
| Clostridium perfringens | Delta toxin | GM2(NeuAc) | Monosialoglycosphingolipids | GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 12628483 | |
| Clostridium perfringens | Delta toxin | GM2(NeuAc) | Monosialoglycosphingolipids | GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 15973004 | |
| Clostridium perfringens | Unknown | GM2(NeuAc) | Monosialoglycosphingolipids | GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 12628483 | |
| Clostridium perfringens | Unknown | GM2(NeuAc) | Monosialoglycosphingolipids | GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 15973004 | |
| Clostridium perfringens | Unknown | GM2(NeuAc) | Monosialoglycosphingolipids | GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 6260669 | |
| Clostridium tetani | Tetanus toxin | GD1b | Disialoglycosphingolipids | Brain membrane | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 6257717 |
| Clostridium tetani | Unknown | GD1b | Disialoglycosphingolipids | Brain membrane | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 6257717 |
| Clostridium tetani | Tetanus toxin | GT1b | Trisialoglycosphingolipids | Brain membrane | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 6257717 |
| Clostridium tetani | Unknown | GT1b | Trisialoglycosphingolipids | Brain membrane | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 6257717 |
| Clostridium tetani | Tetanus toxin (C-fragment) | GD1b | Disialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 9038159 | |
| Clostridium tetani | Tetanus toxin | GD1b | Disialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 7527546 | |
| Clostridium tetani | Unknown | GD1b | Disialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 9038159 |
