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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence ▲ | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Actinomyces viscosus | Unknown | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Most tissues | Gal(b1-1)Cer | Not Binding | 2358461 |
| Mycoplasma pneumoniae | Unknown | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Human colon adenocarcinoma cells (WiDr ) | Gal(b1-1)Cer | Not Binding | 2470753 |
| Actinomyces naeslundii | Unknown | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Most tissues | Gal(b1-1)Cer | Not Binding | 2358461 |
| Escherichia coli | PsaA/B (pH-6 antigen) | Galactosylceramide (hydroxylated/nonhydroxylated fatty acids) | Monoglycosylceramides | Gal(b1-1)Cer | Binding | 9712817 | |
| Rotavirus | Unknown | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Gal(b1-1)Cer | Not Binding | 11160731 | |
| Yersinia pestis | PsaA/B (pH-6 antigen) | Galactosylceramide (nonhydroxylated fatty acids) | Monoglycosylceramides | Gal(b1-1)Cer | Not Binding | 9712817 | |
| Yersinia pestis | PsaA/B (pH-6 antigen) | Galactosylceramide (hydroxylated fatty acids) | Monoglycosylceramides | Gal(b1-1)Cer | Binding | 9712817 | |
| Escherichia coli | F1C | Galactosylceramide (hydroxylated fatty acids) | Monoglycosylceramides | Gal(b1-1)Cer | Binding | 10816509 | |
| Propionibacterium granulosum | Lectin-like proteins (adhesin) | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Gal(b1-1)Cer | Not Binding | 2468365 | |
| Propionibacterium freudenreichii | Unknown | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Gal(b1-1)Cer | Not Binding | 2435422 | |
| Propionibacterium granulosum | Unknown | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Gal(b1-1)Cer | Not Binding | 2435422 | |
| Actinobacillus pleuropneumoniae | LPS | Galactosylceramide (hydroxylated/nonhydroxylated fatty acids) | Monoglycosylceramides | Gal(b1-1)Cer | Binding | 10496867 | |
| Human immunodeficiency virus | Unknown | Galactosylceramide (or derivative) | Monoglycosylceramides | Human colon epithelial HT29 cells | Gal(b1-1)Cer | Binding | 1378511 |
| Actinomyces naeslundii | Type-2 fimbrial lectins (130-kDa glycoprotein) | unnamed ligand | Oligosaccharides | Polymorphonuclear leukocytes (PMNs) | Gal(b1-3)GalNAc | Binding | 7790078 |
| Fusobacterium nucleatum | Lectin-like proteins (adhesin) | unnamed ligand | Oligosaccharides | Gal(b1-3)GalNAc | Binding | 1894623 | |
| Actinomyces naeslundii | Unknown | unnamed ligand | Oligosaccharides | Gal(b1-3)GalNAc | Binding | 12628483 | |
| Actinomyces viscosus | Unknown | SSEA-3 (GSL) (Galactosyl globoside; Gb5) | Oligoglycosylceramides | Vero cells | Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Shigella dysenteriae | B subunit | SSEA-3 (GSL) (Galactosyl globoside; Gb5) | Oligoglycosylceramides | Human kidney | Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 3543013 |
| Actinomyces naeslundii | Unknown | SSEA-3 (GSL) (Galactosyl globoside; Gb5) | Oligoglycosylceramides | Vero cells | Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 2358461 |
| Shigella dysenteriae | Shiga toxin | SSEA-3 (GSL) (Galactosyl globoside; Gb5) | Oligoglycosylceramides | Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2435422 | |
| Escherichia coli | Unknown | SSEA-3 (GSL) (Galactosyl globoside; Gb5) | Oligoglycosylceramides | Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 2435422 | |
| Shigella dysenteriae | Unknown | SSEA-3 (GSL) (Galactosyl globoside; Gb5) | Oligoglycosylceramides | Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2435422 | |
| Parvovirus | Unknown | SSEA-3 (GSL) (Galactosyl globoside; Gb5) | Oligoglycosylceramides | Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 12628483 | |
| Bordetella pertussis | Adhesins | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Human lung, Human trachea | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 1918002 |
| Burkholderia cepacia | Lectin-like proteins (adhesin) | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Sputa of cystic fibrosis patients | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 8606110 |
