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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence ▼ | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Escherichia coli | FimH | Mannotriose | Oligosaccharides | Man(a1-3)[Man(a1-6)]Man | Binding | 12010488 | |
| Escherichia coli | Type 1-pili | Mannotriose | Oligosaccharides | Man(a1-3)[Man(a1-6)]Man | Binding | 12010488 | |
| Escherichia coli | Type 1-fimbriae | trisaccharide: Man(a1-3)Man(b1-4)GlcNAc | Oligosaccharides | Patient with urinary tract infection | Man(a1-3)Man(b1-4)GlcNAc | Binding | 6138149 |
| Escherichia coli | Type 1-fimbriae | trisaccharide: Man(a1-3)Man(b1-4)GlcNAc | Oligosaccharides | Man(a1-3)Man(b1-4)GlcNAc | Binding | 16564136 | |
| Escherichia coli | Type 1-fimbriae | unnamed ligand | Oligosaccharides | Urine | Man(a1-3)Man(a1-6)Man | Binding | 16564136 |
| Trypanosoma cruzi | CBPs (carbohydrate-binding proteins) | High mannose glycans containig the Manα1-2Manα1-6Manα1-6 structure | Saccharides | Man(a1-2)Man(a1-6)Man(a1-6) | Binding | 11555616 | |
| Streptococcus pneumoniae | Adhesins | D-Mannose | Monosaccharides | Type-II lung cells, Vascular endothelial cells | Man | Binding | 7752878 |
| Escherichia coli | Type 1-pili | D-Mannose | Monosaccharides | Bladder epithelium | Man | Binding | 12010488 |
| Rabies virus | Unknown | Mannose | Monosaccharides | Chicken embryo related cells | Man | Binding | 3583664 |
| Escherichia coli | FimCH-chaperone-adhesin complex | D-Mannose | Monosaccharides | Bladder epithelium | Man | Binding | 12010488 |
| Klebsiella pneumoniae | Unknown | Mannose | Monosaccharides | Respiratory tract | Man | Binding | 16564136 |
| Salmonella typhimurium | Unknown | Mannose | Monosaccharides | Intestinal cells | Man | Binding | 16564136 |
| Vibrio cholerae | MSHA (mannose/glucose-specific hemagglutinin) | Mannose | Monosaccharides | Patient with acute watery diarrhea | Man | Binding | 10219594 |
| Escherichia coli | FimH | Mannose oligosaccharides | Oligosaccharides | Eukaryotic cells | Man | Binding | 12640357 |
| Escherichia coli | Type 1-fimbriae | Mannose-derived neoglycoproteins and dendrimers | Glycoproteins | Man | Binding | 16564136 | |
| Ralstonia solanacearum | RS-IIL (homologous to PA-IIL) | Mannose | Monosaccharides | Man | Binding | 16762477 | |
| Pseudomonas aeruginosa | PA-IIL | D-Mannose | Monosaccharides | Man | Binding | 10967261 | |
| Pseudomonas aeruginosa | PA-IIL (47-kDa) | D-Mannose | Monosaccharides | Man | Binding | 15049333 | |
| Klebsiella pneumoniae | Type 1-fimbriae | Mannose | Monosaccharides | Man | Binding | 2885220 | |
| Escherichia coli | Type 1-fimbriae (17 kDa subunit) | Mannose | Monosaccharides | Man | Binding | 2885220 | |
| Salmonella spp. | Type 1-fimbriae | Mannose | Monosaccharides | Man | Binding | 2885220 | |
| Pseudomonas aeruginosa | Type 1-fimbriae | Mannose | Monosaccharides | Man | Binding | 2885220 | |
| Serratia marcescens | Type 1-fimbriae | Mannose | Monosaccharides | Man | Binding | 2885220 | |
| Shigella flexneri | Type 1-fimbriae | Mannose | Monosaccharides | Man | Binding | 2885220 | |
| Escherichia coli | FimH | Mannose oligosaccharides | Oligosaccharides | Man | Binding | 10341176 |
