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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature ▼ | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Neisseria gonorrhoeae | Adhesins | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Mucos membranes of the genitourinary tract/rectum/oropharynx/conjunctiva | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2115881 |
| Legionella pneumophila | Adhesins | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Human epithelial cells (respiratory tract) | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 14687561 |
| Escherichia coli | F1C | isoGb3 (Isoglobotriaosylceramide; iGb3) | Oligoglycosylceramides | Cat intestine | Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 11877427 |
| Streptococcus pneumoniae | CbpA; SpsA; PbcA; PspC (CBPs) | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Cytokine activated epithelial and endothelial cells | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 10341176 |
| Neisseria gonorrhoeae | Lectin-like proteins (adhesin) | isoGb3 (Isoglobotriaosylceramide; iGb3) | Oligoglycosylceramides | Gonorrhoeae patients | Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2468365 |
| Neisseria gonorrhoeae | Lectin-like proteins (adhesin) | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Gonorrhoeae patients | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 2468365 |
| Pseudomonas aeruginosa | exoenzyme S | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Epithelial cells | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9224879 |
| Escherichia coli | Adhesins | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | Human erythrocytes, Human uroepithelial cells | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 7037645 |
| Propionibacterium granulosum | Lectin-like proteins (adhesin) | isoGb3 (Isoglobotriaosylceramide; iGb3) | Oligoglycosylceramides | Human skin | Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2468365 |
| Propionibacterium granulosum | Lectin-like proteins (adhesin) | Fucosyl Asialo GM1 | Oligoglycosylceramides | Human skin | Fuc(a1-2)Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 2468365 |
| Propionibacterium granulosum | Lectin-like proteins (adhesin) | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Human skin | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 2468365 |
| Propionibacterium granulosum | Lectin-like proteins (adhesin) | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Human skin | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2468365 |
| Escherichia coli | PapG (class II) | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | Epithelial cells in human urinary tract | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9007266 |
| Escherichia coli | Unknown | CD77 (Globotriaosylceramide; Gb3) | Oligoglycosylceramides | Germinal center B lymphocytes, Burkitt's lymphoma cells | Gal(a1-4)Gal | Binding | 7516406 |
| Actinomyces viscosus | Unknown | isoGb3 (Isoglobotriaosylceramide; iGb3) | Oligoglycosylceramides | Dog small intestine | Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2358461 |
| Actinomyces viscosus | Unknown | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Human brain | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 2358461 |
| Actinomyces viscosus | Unknown | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Dog small intestine | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2358461 |
| Mycoplasma pneumoniae | Unknown | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Human colon adenocarcinoma cells (WiDr ) | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2470753 |
| Mycoplasma pneumoniae | Unknown | Alpha-Galactosyl paragloboside | Oligoglycosylceramides | Human colon adenocarcinoma cells (WiDr ) | Gal(a1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2470753 |
| Lactobacillus johnsonii | Unknown | isoGb3 (Isoglobotriaosylceramide; iGb3) | Oligoglycosylceramides | Dog small intestine | Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 11087711 |
| Lactobacillus johnsonii | Unknown | Fucosyl Asialo GM1 | Oligoglycosylceramides | Mouse small intestine | Fuc(a1-2)Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 11087711 |
| Lactobacillus johnsonii | Unknown | nLc6 (Neolactohexaosylceramide) | Oligoglycosylceramides | Rabbit thymus | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 11087711 |
| Lactobacillus johnsonii | Unknown | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Guinea pig erythrocytes | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 11087711 |
| Lactobacillus johnsonii | Unknown | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Human erythrocytes | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 11087711 |
| Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | Fucosyl Asialo GM1 | Oligoglycosylceramides | Mouse intestine | Fuc(a1-2)Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9228091 |
