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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature ▼ | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Human granulocytes | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 9228091 |
| Shigella dysenteriae | B subunit | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | Human erythrocytes | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 3543013 |
| Pseudomonas aeruginosa | Unknown | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Cystic fibrosis patients | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 15973004 |
| Pseudomonas aeruginosa | Unknown | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Lung | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 3124753 |
| Lactobacillus casei | Unknown | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Intestinal tract | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 8912650 |
| Pseudomonas aeruginosa | Flagellin | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Epithelial cells | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9224879 |
| Candida albicans | "Extracellular polymeric material, acid proteinase, chitin" | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Human buccal epihelial cells (BECs) | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 8005674 |
| Actinomyces naeslundii | Unknown | isoGb3 (Isoglobotriaosylceramide; iGb3) | Oligoglycosylceramides | Dog small intestine | Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2358461 |
| Actinomyces naeslundii | Unknown | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Human brain | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 2358461 |
| Actinomyces naeslundii | Unknown | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Dog small intestine | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2358461 |
| Actinomyces naeslundii | Unknown | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | Human erythrocytes | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 2358461 |
| Actinomyces naeslundii | Unknown | isoGb4 (Isoglobotetraosylceramide; iGb4) | Oligoglycosylceramides | Rat colon carcinoma | GalNAc(b1-3)Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2358461 |
| Pseudomonas cepacia | Unknown | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Lung | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 3124753 |
| Actinomyces naeslundii | Type-2 fimbrial lectins | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 3804448 | |
| Helicobacter mustelae | Lectin-hemagglutinin adhesins | isoGb3 (Isoglobotriaosylceramide; iGb3) | Oligoglycosylceramides | Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 12704182 | |
| Helicobacter bilis | Lectin-hemagglutinin adhesins | isoGb3 (Isoglobotriaosylceramide; iGb3) | Oligoglycosylceramides | Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 12704182 | |
| Helicobacter pylori | Lectin-hemagglutinin adhesins | isoGb3 (Isoglobotriaosylceramide; iGb3) | Oligoglycosylceramides | Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 12704182 | |
| Escherichia coli | K88ab/K88ac/K88ad | nLc6 (Neolactohexaosylceramide) | Oligoglycosylceramides | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 11953368 | |
| Escherichia coli | K88ab/K88ac/K88ad | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 11953368 | |
| Escherichia coli | K88ab/K88ac/K88ad | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 11953368 | |
| Escherichia coli | PapG (class III) | Gb5 (Forssman glycolipid) | Oligoglycosylceramides | GalNAc(a1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 11454740 | |
| Escherichia coli | K99-fimbriae | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 12628483 | |
| Helicobacter hepaticus | Lectin-hemagglutinin adhesins | isoGb3 (Isoglobotriaosylceramide; iGb3) | Oligoglycosylceramides | Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 12704182 | |
| Helicobacter felis | Lectin-hemagglutinin adhesins | isoGb3 (Isoglobotriaosylceramide; iGb3) | Oligoglycosylceramides | Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 12704182 | |
| Escherichia coli | PsaA/B (pH-6 antigen) | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9712817 |
