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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID ▼ |
|---|---|---|---|---|---|---|---|
| Neisseria gonorrhoeae | N-methylphenyl-alanine pili | Glucosamine-galactose carbohydrate | Disaccharides | Binding | 12640357 | ||
| Streptococcus pneumoniae | PsaA (Lary family) | N-acetylhexosamine-galactose | Disaccharides | Binding | 12640357 | ||
| Bordetella pertussis | Pertactin | Integrins | Glycoproteins | Binding | 12640357 | ||
| Streptococcus pneumoniae | CBPs (choline-binding proteins) | Sialic acid | Monosaccharides | Cytokine-activated cells | Binding | 12640357 | |
| Enterococcus faecalis | EfaA (Lary family) | D-Galactose-containing residues | Saccharides | Gal | Binding | 12640357 | |
| Streptococcus pyogenes | Sfbl (Antigen I/II) | Fibronectin | Glycoproteins | Respiratory epithelial cells | Binding | 12640357 | |
| Streptococcus pyogenes | Protein F (Antigen I/II) | Fibronectin | Glycoproteins | Respiratory epithelial cells | Binding | 12640357 | |
| Escherichia coli | SafS | α-sialyl-2-3-β-galactose | Disaccharides | Binding | 12640357 | ||
| Streptococcus gordonii | CshaB (Antigen I/II) | Fibronectin | Glycoproteins | Binding | 12640357 | ||
| Klebsiella pneumoniae | MrkD-pili | Collagen (type V) | Glycoproteins | Binding | 12640357 | ||
| Staphylococcus aureus | FnbB | Fibronectin | Glycoproteins | Binding | 12640357 | ||
| Streptococcus pneumoniae | PspC (Lary family) (alias: SpsA/CbpA/PbcA/Hic) | C3 and complement factor H | Glycoproteins | Binding | 12640357 | ||
| Streptococcus pneumoniae | PspC (Lary family) (alias: SpsA/CbpA/PbcA/Hic) | IgA | Glycoproteins | Binding | 12640357 | ||
| Staphylococcus aureus | FnbA | Fibronectin | Glycoproteins | Binding | 12640357 | ||
| Streptococcus gordonii | CshA (Antigen I/II) | Fibronectin | Glycoproteins | Binding | 12640357 | ||
| Vibrio cholerae | N-methylphenyl-alanine pili | Fucose ve mannose carbohydrate | Saccharides | Binding | 12640357 | ||
| Escherichia coli | Heat-labile enterotoxin | GD1b | Disialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 12628483 | |
| Escherichia coli | Heat-labile enterotoxin | GD3(NeuAc) | Disialoglycosphingolipids | NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 12628483 | |
| Rotavirus | Unknown | GD1a | Disialoglycosphingolipids | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 12628483 | |
| Escherichia coli | K99-fimbriae | GD1b | Disialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 12628483 | |
| Escherichia coli | K99-fimbriae | GD3(NeuAc) | Disialoglycosphingolipids | NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 12628483 | |
| Escherichia coli | Unknown | GD1b | Disialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 12628483 | |
| Escherichia coli | Unknown | GD3(NeuAc) | Disialoglycosphingolipids | NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 12628483 | |
| Borrelia burgdorferi | Unknown | GD1a | Disialoglycosphingolipids | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 12628483 | |
| Sendai virus | Unknown | GD1a | Disialoglycosphingolipids | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 12628483 |
