PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
Source | Last Updated |
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Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding ▲ | PubMed ID |
---|---|---|---|---|---|---|---|
Legionella pneumophila | Adhesins | unnamed ligand | Oligosaccharides | Human epithelial cells (respiratory tract) | Gal(b1-4)GlcNAc | Binding | 14687561 |
Escherichia coli | FimH | Mannose oligosaccharides | Oligosaccharides | Eukaryotic cells | Man | Binding | 12640357 |
Haemophilus influenzae | Unknown | Tetrasaccharides | Oligosaccharides | Respiratory tract | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc | Binding | 16564136 |
Campylobacter jejuni | Unknown | unnamed ligand | Oligosaccharides | Intestinal cells | Fuc(a1-2)Gal(b1-4)GlcNAc | Binding | 16564136 |
Pseudomonas aeruginosa | Unknown | unnamed ligand | Oligosaccharides | Respiratory tract | Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc | Binding | 16564136 |
Streptococcus pneumoniae | Unknown | unnamed ligand | Oligosaccharides | Chinchilla tubotympanum | Gal(b1-4)GlcNAc(b1-3)Gal(b | Binding | 1298868 |
Streptococcus pneumoniae | Unknown | Tetrasaccharides | Oligosaccharides | Respiratory tract | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc | Binding | 16564136 |
Streptococcus suis | Unknown | unnamed ligand | Oligosaccharides | Respiratory tract | Gal(a1-4)Gal(b1-4)Glc | Binding | 16564136 |
Neisseria meningitidis | Unknown | Tetrasaccharides | Oligosaccharides | Respiratory tract | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc | Binding | 16564136 |
Actinomyces naeslundii | Unknown | unnamed ligand | Polyglycosylceramides | Rat small intestine | GalNAc(b1-3)[Gal(a1-3)]nGal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 2358461 |
Streptococcus pneumoniae | Adhesins | GlcNAc(b1-3)Gal sequence | Saccharides | Human endothelial cells | GlcNAc(b1-3)Gal | Binding | 6886624 |
Actinomyces naeslundii | Type 2-fimbriae | β-linked galactosamine | Saccharides | Buccae | GalNAc(b 2:2 | Binding | 9712794 |
Actinomyces naeslundii | Type 2-fimbriae | β-linked galactosamine | Saccharides | Plaque | GalNAc(b 2:2 | Binding | 9712794 |
Actinomyces odontolyticus | Type 2-fimbriae | β-linked galactosamine | Saccharides | Buccae | GalNAc(b 2:2 | Binding | 9712794 |
Escherichia coli | 20K-fimbriae | GlcNAc sequence | Saccharides | Human colon carcinoma Caco-2 cell line | GlcNAc | Binding | 8557360 |
Actinomyces odontolyticus | Type 2-fimbriae | β-linked galactosamine | Saccharides | Plaque | GalNAc(b 2:2 | Binding | 9712794 |
Escherichia coli | 18-kDa fimbrial adhesin | Galactose derivatives | Saccharides | HEp-2 cells | Gal | Binding | 11368522 |
Escherichia coli | F1C | unnamed ligand | Saccharides | Urine | GalNAc(b1-4)Gal(b | Binding | 16564136 |
Rotavirus | Unknown | Lactosylceramide (t18:0-h16:0-h24:0) | Diosylceramides | Gal(b1-4)Glc(b1-1)Cer | Binding | 11160731 | |
Pseudomonas aeruginosa | PA-IL (51-kDa) | Melibiose | Disaccharides | Gal(a1-6)Glc | Binding | 15049333 | |
Pseudomonas aeruginosa | PA-IL (51-kDa) | Galactose-alpha-1,3-galactose | Disaccharides | Gal(a1-3)Gal | Binding | 15049333 | |
Pseudomonas aeruginosa | PA-IL (51-kDa) | Galactose-alpha-1,4-galactose | Disaccharides | Gal(a1-4)Gal | Binding | 15049333 | |
Pseudomonas aeruginosa | PA-IIL | Blood group H antigen | Disaccharides | Fuc(a1-2)Gal | Binding | 16762477 | |
Pseudomonas aeruginosa | PA-IL | Melibiose | Disaccharides | Gal(a1-6)Glc | Binding | 10967261 | |
Ralstonia solanacearum | RSL (30-kDa proteins) | Blood group H antigen | Disaccharides | Fuc(a1-2)Gal | Binding | 16762477 |
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Last updated: August 19, 2024