PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
Source | Last Updated |
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Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
Species ▲ | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
---|---|---|---|---|---|---|---|
Escherichia coli | FimH | Collagen | Glycoproteins | Binding | 12010488 | ||
Escherichia coli | Type 1-pili | CD48 | Glycoproteins | Binding | 12010488 | ||
Escherichia coli | Type 1-pili | Uroplakins 1a and 1b containing a single N-linked carbohydrate of the high-mannose type | Glycoproteins | Binding | 12010488 | ||
Escherichia coli | Type 1-pili | Collagen | Glycoproteins | Binding | 12010488 | ||
Escherichia coli | (class I/II/III) | Globo-A | Oligoglycosylceramides | Binding | 7721812 | ||
Escherichia coli | P-fimbriae | Globo-A | Oligoglycosylceramides | Binding | 7721812 | ||
Escherichia coli | PrsG (class III) | DSGG (Disialosyl galactosyl globoside, disialyl Gb5) | Disialoglycosphingolipids | Human kidney tissues | NeuAc(a2-3)Gal(b1-3)[NeuAc(a2-6)]GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9673272 |
Escherichia coli | PapG (class I) | DSGG (Disialosyl galactosyl globoside, disialyl Gb5) | Disialoglycosphingolipids | Human kidney tissues | NeuAc(a2-3)Gal(b1-3)[NeuAc(a2-6)]GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9673272 |
Escherichia coli | P-fimbriae | DSGG (Disialosyl galactosyl globoside, disialyl Gb5) | Disialoglycosphingolipids | Human kidney tissues | NeuAc(a2-3)Gal(b1-3)[NeuAc(a2-6)]GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9673272 |
Escherichia coli | PapG (class II) | DSGG (Disialosyl galactosyl globoside, disialyl Gb5) | Disialoglycosphingolipids | Human kidney tissues | NeuAc(a2-3)Gal(b1-3)[NeuAc(a2-6)]GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9673272 |
Escherichia coli | S-fimbriae | NeuAcα3Galβ-containing glycoproteins | Glycoproteins | Lumenal surfaces of the vascular endothelium in the neonatal rat brain | NeuAc(a2-3)Gal(b | Binding | 15973004 |
Escherichia coli | SfaS | NeuAcα3Galβ-containing glycoproteins | Glycoproteins | Lumenal surfaces of the vascular endothelium in the neonatal rat brain | NeuAc(a2-3)Gal(b | Binding | 15973004 |
Escherichia coli | PrsG (class III) | SSEA-4 (GSL) (Sialosyl galactosyl globoside; SGG; sialyl Gb5) | Monosialoglycosphingolipids | Human kidney tissues | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9673272 |
Escherichia coli | PapG (class I) | SSEA-4 (GSL) (Sialosyl galactosyl globoside; SGG; sialyl Gb5) | Monosialoglycosphingolipids | Human kidney tissues | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9673272 |
Escherichia coli | P-fimbriae | SSEA-4 (GSL) (Sialosyl galactosyl globoside; SGG; sialyl Gb5) | Monosialoglycosphingolipids | Human kidney tissues | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9673272 |
Escherichia coli | PapG (class II) | SSEA-4 (GSL) (Sialosyl galactosyl globoside; SGG; sialyl Gb5) | Monosialoglycosphingolipids | Human kidney tissues | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9673272 |
Escherichia coli | F1C | GM3(NeuAc) | Monosialoglycosphingolipids | Human brain | NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11877427 |
Escherichia coli | CFA/1 | Sialic acid (α2,8) | Saccharides | Intestinal cells | NeuAc(a2-8) | Binding | 16564136 |
Escherichia coli | S-fimbriae (SfaA) | Galactosyl sulfatide | Sulfoglycosphingolipids | Brain endothelial cells | Gal(3SO4)(b1-1)Cer | Binding | 8098039 |
Escherichia coli | F1C | Sulfatide (CSE) | Sulfoglycosphingolipids | Porcine intestine | HSO3(-3)Gal(b1-1)Cer | Not Binding | 11877427 |
Escherichia coli | K88ab/K88ac/K88ad | GD1a | Disialoglycosphingolipids | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11953368 | |
Escherichia coli | PsaA/B (pH-6 antigen) | GD1a | Disialoglycosphingolipids | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9712817 | |
Escherichia coli | Heat-labile enterotoxin (type II(LT-Iia)) | GD2 | Disialoglycosphingolipids | GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 3290106 | |
Escherichia coli | Heat-labile enterotoxin | GD1a | Disialoglycosphingolipids | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7527546 | |
Escherichia coli | Heat-labile enterotoxin | GD2 | Disialoglycosphingolipids | GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 7527546 |
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Last updated: August 19, 2024