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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species ▲ | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Escherichia coli | K88ad | Lactosylceramide (Lactocerebroside) | Diosylceramides | Gal(b1-4)Glc(b1-1)Cer | Binding | 11953368 | |
| Escherichia coli | Unknown | Gb2 (Galabiosylceramide) | Diosylceramides | Gal(a1-4)Gal(b1-1)Cer | Binding | 2435422 | |
| Escherichia coli | PsaA/B (pH-6 antigen) | Galactosylceramide (hydroxylated/nonhydroxylated fatty acids) | Monoglycosylceramides | Gal(b1-1)Cer | Binding | 9712817 | |
| Escherichia coli | F1C | Glucosylceramide | Monoglycosylceramides | Glc(b1-1)Cer | Binding | 10816509 | |
| Escherichia coli | F1C | Galactosylceramide (hydroxylated fatty acids) | Monoglycosylceramides | Gal(b1-1)Cer | Binding | 10816509 | |
| Escherichia coli | NeuC protein of K1 capsule (UDP GlcNAc 2-epimerase)) | N-Acetylglucosamine | Monosaccharides | GlcNAc | Not Binding | 14729696 | |
| Escherichia coli | K88ab/K88ac/K88ad | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11953368 | |
| Escherichia coli | K88ab/K88ac/K88ad | Lactotriaosylceramide (Lc3) | Oligoglycosylceramides | GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 11953368 | |
| Escherichia coli | K88ab/K88ac/K88ad | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 11953368 | |
| Escherichia coli | K88ab/K88ac/K88ad | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 11953368 | |
| Escherichia coli | PsaA/B (pH-6 antigen) | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9712817 | |
| Escherichia coli | PsaA/B (pH-6 antigen) | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9712817 | |
| Escherichia coli | Fim2 (H1/H2) | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 12628483 | |
| Escherichia coli | P-fimbriae | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 7721812 | |
| Escherichia coli | P-fimbriae | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7721812 | |
| Escherichia coli | P-fimbriae | unnamed ligand | Oligoglycosylceramides | Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-6)[Gal(b1-3)]GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 7721812 | |
| Escherichia coli | P-fimbriae | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 15973004 | |
| Escherichia coli | P-pili | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 11953368 | |
| Escherichia coli | Shiga-like toxin (Stx1) | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 3284526 | |
| Escherichia coli | Verotoxin | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 3298243 | |
| Escherichia coli | Shiga-like toxin (Stx1) | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 18541402 | |
| Escherichia coli | Shiga toxin (Stx1/Stx2/Stx2c/Stx2d) | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 11179385 | |
| Escherichia coli | Heat-labile enterotoxin | H5 type 2 pentaglycosylceramide (neolacto-series) | Oligoglycosylceramides | Fuc(a1-2)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7527546 | |
| Escherichia coli | Heat-labile enterotoxin | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7527546 | |
| Escherichia coli | Heat-labile enterotoxin | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7527546 |
