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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence ▲ | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Neisseria gonorrhoeae | Lectin-like proteins (adhesin) | H5 type 1 pentaglycosylceramide (lacto-series) | Oligoglycosylceramides | Gonorrhoeae patients | Fuc(a1-2)Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2468365 |
| Propionibacterium granulosum | Lectin-like proteins (adhesin) | H5 type 1 pentaglycosylceramide (lacto-series) | Oligoglycosylceramides | Human skin | Fuc(a1-2)Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2468365 |
| Propionibacterium freudenreichii | Unknown | H5 type 1 pentaglycosylceramide (lacto-series) | Oligoglycosylceramides | Fuc(a1-2)Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2435422 | |
| Propionibacterium granulosum | Unknown | H5 type 1 pentaglycosylceramide (lacto-series) | Oligoglycosylceramides | Fuc(a1-2)Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2435422 | |
| Norovirus | Unknown | Blood group H1 antigen (HSA) | Glycoproteins | Human serum albumin | Fuc(a1-2)Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(c)-APD | Binding | 19054801 |
| Helicobacter pylori | BabA (blood group antigen binding adhesin) | Blood group H1 antigen (HSA) | Glycoproteins | Fuc(a1-2)Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(c)-APD | Binding | 15273394 | |
| Helicobacter pylori | Unknown | unnamed ligand | Oligosaccharides | Fuc(a1-2)Gal(b1-3)[Fuc(a1-4)]Gal | Binding | 16564136 | |
| Norovirus | Unknown | Lewis b (Leb-HSA) | Glycoproteins | Human serum albumin | Fuc(a1-2)Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(c)-APD | Binding | 19054801 |
| Campylobacter jejuni | Unknown | unnamed ligand | Oligosaccharides | Intestinal cells | Fuc(a1-2)Gal(b1-4)GlcNAc | Binding | 16564136 |
| Actinomyces viscosus | Unknown | unnamed ligand | Oligoglycosylceramides | Dog small intestine | Fuc(a1-2)Gal(b1-4)GlcNAc(b1-3)Gal(b1-3)Glc(b1-1)Cer | Not Binding | 2358461 |
| Actinomyces naeslundii | Unknown | unnamed ligand | Oligoglycosylceramides | Dog small intestine | Fuc(a1-2)Gal(b1-4)GlcNAc(b1-3)Gal(b1-3)Glc(b1-1)Cer | Not Binding | 2358461 |
| Escherichia coli | F1C | H5 type 2 pentaglycosylceramide (neolacto-series) | Oligoglycosylceramides | Human erythrocytes | Fuc(a1-2)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11877427 |
| Neisseria gonorrhoeae | Lectin-like proteins (adhesin) | H5 type 2 pentaglycosylceramide (neolacto-series) | Oligoglycosylceramides | Gonorrhoeae patients | Fuc(a1-2)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2468365 |
| Propionibacterium granulosum | Lectin-like proteins (adhesin) | H5 type 2 pentaglycosylceramide (neolacto-series) | Oligoglycosylceramides | Human skin | Fuc(a1-2)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2468365 |
| Lactobacillus johnsonii | Unknown | H5 type 2 pentaglycosylceramide (neolacto-series) | Oligoglycosylceramides | Human erythrocytes | Fuc(a1-2)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11087711 |
| Vibrio cholerae | Cholera toxin | H5 type 2 pentaglycosylceramide (neolacto-series) | Oligoglycosylceramides | Fuc(a1-2)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7527546 | |
| Escherichia coli | Heat-labile enterotoxin | H5 type 2 pentaglycosylceramide (neolacto-series) | Oligoglycosylceramides | Fuc(a1-2)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7527546 | |
| Vibrio cholerae | Unknown | H5 type 2 pentaglycosylceramide (neolacto-series) | Oligoglycosylceramides | Fuc(a1-2)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7527546 | |
| Escherichia coli | Unknown | H5 type 2 pentaglycosylceramide (neolacto-series) | Oligoglycosylceramides | Fuc(a1-2)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7527546 | |
| Propionibacterium freudenreichii | Unknown | H5 type 2 pentaglycosylceramide (neolacto-series) | Oligoglycosylceramides | Fuc(a1-2)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2435422 | |
| Propionibacterium granulosum | Unknown | H5 type 2 pentaglycosylceramide (neolacto-series) | Oligoglycosylceramides | Fuc(a1-2)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2435422 | |
| Escherichia coli | K88ab/K88ac/K88ad | Fuc-nLc6 (VI2) | Oligoglycosylceramides | Fuc(a1-2)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11953368 | |
| Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | unnamed ligand | Sialoglycosphingolipids | Human erythrocytes | Fuc(a1-2)Gal(b1-4)GlcNAc(b1-6)[NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)]Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9228091 |
| Clostridium difficile | Toxin A | α-Gal on Fab of IgA(κ) MAb | Glycoproteins | Mouse | Gal | Binding | 9573079 |
| Clostridium difficile | Toxin A | α-Gal on Fab of IgM(λ) MAb | Glycoproteins | Mouse | Gal | Binding | 9573079 |
