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Repository for lectin-assisted multimodality data
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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding ▼ | PubMed ID |
|---|---|---|---|---|---|---|---|
| Streptococcus pneumoniae | Unknown | unnamed ligand | Oligosaccharides | Chinchilla tubotympanum | Gal(b1-4)GlcNAc(b1-3)Gal(b | Binding | 1298868 |
| Streptococcus pneumoniae | Unknown | Tetrasaccharides | Oligosaccharides | Respiratory tract | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc | Binding | 16564136 |
| Streptococcus suis | Unknown | unnamed ligand | Oligosaccharides | Respiratory tract | Gal(a1-4)Gal(b1-4)Glc | Binding | 16564136 |
| Neisseria meningitidis | Unknown | Tetrasaccharides | Oligosaccharides | Respiratory tract | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc | Binding | 16564136 |
| Actinomyces naeslundii | Unknown | unnamed ligand | Polyglycosylceramides | Rat small intestine | GalNAc(b1-3)[Gal(a1-3)]nGal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 2358461 |
| Streptococcus pneumoniae | Adhesins | GlcNAc(b1-3)Gal sequence | Saccharides | Human endothelial cells | GlcNAc(b1-3)Gal | Binding | 6886624 |
| Actinomyces naeslundii | Type 2-fimbriae | β-linked galactosamine | Saccharides | Buccae | GalNAc(b 2:2 | Binding | 9712794 |
| Actinomyces naeslundii | Type 2-fimbriae | β-linked galactosamine | Saccharides | Plaque | GalNAc(b 2:2 | Binding | 9712794 |
| Actinomyces odontolyticus | Type 2-fimbriae | β-linked galactosamine | Saccharides | Buccae | GalNAc(b 2:2 | Binding | 9712794 |
| Escherichia coli | 20K-fimbriae | GlcNAc sequence | Saccharides | Human colon carcinoma Caco-2 cell line | GlcNAc | Binding | 8557360 |
| Actinomyces odontolyticus | Type 2-fimbriae | β-linked galactosamine | Saccharides | Plaque | GalNAc(b 2:2 | Binding | 9712794 |
| Escherichia coli | 18-kDa fimbrial adhesin | Galactose derivatives | Saccharides | HEp-2 cells | Gal | Binding | 11368522 |
| Escherichia coli | F1C | unnamed ligand | Saccharides | Urine | GalNAc(b1-4)Gal(b | Binding | 16564136 |
| Helicobacter mustelae | Lectin-hemagglutinin adhesins | Acid glycosphingolipids | Acidic Glycosphingolipids | Human granulocytes | Binding | 12704182 | |
| Helicobacter pylori | Lectin-hemagglutinin adhesins | Acid glycosphingolipids | Acidic Glycosphingolipids | Human granulocytes | Binding | 12704182 | |
| Helicobacter hepaticus | Lectin-hemagglutinin adhesins | Acid glycosphingolipids | Acidic Glycosphingolipids | Human granulocytes | Binding | 12704182 | |
| Helicobacter pylori | HPNAP (neutrophil-activating protein of H. pylori) | Acid glycosphingolipids | Acidic Glycosphingolipids | Human neutrophil granulocytes | Binding | 11087709 | |
| Influenza virus | Hemagglutinin | Human and avian receptors containing sialylated glycoconjugates | Glycoconjugates | Airways | Binding | 18809496 | |
| Histoplasma capsulatum | Lectin-like component | Galactosylated surface molecules (mainly β-anomer) | Glycoconjugates | Murine macrophages | Binding | 19547878 | |
| Influenza virus | Hemagglutinin H1(1934) | Human and avian receptors containing sialylated glycoconjugates | Glycoconjugates | Airways | Binding | 18809496 | |
| Paramyxovirus | Hemagglutinin H1(1934) | Human and avian receptors containing sialylated glycoconjugates | Glycoconjugates | Airways | Binding | 18809496 | |
| Escherichia coli | Type 1-fimbriae | β-D-glycosides | Glycoconjugates | Patient with urinary tract infection | Binding | 6138149 | |
| Plasmodium falciparum | Unknown | Neuraminidase-insensitive, trypsin sensitive carbohydrate ligand | Glycoconjugates | Molecules on the erythrocyte membrane (other than glycophorins A and B) | Binding | 3308959 | |
| Listeria monocytogenes | Unknown | α-GalCer/CD1d tetramers | Glycoconjugates | V[alpha]14+ NK1.1- T cells in infected liver of mice | Binding | 16988270 | |
| Clostridium tetani | Tetanus neurotoxin | Polysialogangliosides and other acidic lipids | Glycolipids | Presynaptic membrane of neuromuscular junction | Binding | 7527117 |
