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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding ▼ | PubMed ID |
|---|---|---|---|---|---|---|---|
| Herpes simplex virus | Unknown | Pentosan polysulfate (PP) | Polysaccharides | Human cervical cells | Binding | 9420059 | |
| Herpes simplex virus | Unknown | Dextran sulfate | Polysaccharides | Human cervical cells | Binding | 9420059 | |
| Neisseria gonorrhoeae | Unknown | Pentosan polysulfate (PP) | Polysaccharides | Human epithelial cells | Binding | 9420059 | |
| Neisseria gonorrhoeae | Unknown | Dextran sulfate | Polysaccharides | Human epithelial cells | Binding | 9420059 | |
| Norovirus | Unknown | Terminal N-Acetylgalactosamine residue in an alpha linkage | Saccharides | Oyster digestive tissues | Binding | 16707048 | |
| Actinomyces naeslundii | Type-2 fimbrial lectins | GD1a | Disialoglycosphingolipids | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 3804448 | |
| Actinomyces naeslundii | Type-2 fimbrial lectins | GD1b | Disialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 3804448 | |
| Escherichia coli | K99 | GD1a(NeuGc) | Disialoglycosphingolipids | NeuGc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuGc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 7849044 | |
| Vibrio cholerae | Cholera toxin | GD1b | Disialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 8574698 | |
| Vibrio cholerae | Cholera toxin | GD1b | Disialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 3290106 | |
| Vibrio cholerae | Cholera toxin | GD1b | Disialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 7527546 | |
| Escherichia coli | Heat-labile enterotoxin (type II(LT-Iia)) | GD1a | Disialoglycosphingolipids | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 3290106 | |
| Escherichia coli | Heat-labile enterotoxin (type II(LT-Iia)) | GD1b | Disialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 3290106 | |
| Vibrio cholerae | Cholera toxin (B subunit(CTB)) | GD1b | Disialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 9038159 | |
| Escherichia coli | Heat-labile enterotoxin (type II(LT-IIb)) | GD1a | Disialoglycosphingolipids | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 3290106 | |
| Clostridium botulinum | Neurotoxin (type B) | GD1a | Disialoglycosphingolipids | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 9712688 | |
| Escherichia coli | Heat-labile enterotoxin (type I(LTh-I)) | GD1b | Disialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 3290106 | |
| Escherichia coli | Heat-labile enterotoxin | GD1b | Disialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 8574698 | |
| Escherichia coli | Heat-labile enterotoxin | GD1b | Disialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 9038159 | |
| Escherichia coli | Heat-labile enterotoxin | GD1b | Disialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 12628483 | |
| Escherichia coli | Heat-labile enterotoxin | GD1b | Disialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 7527546 | |
| Escherichia coli | Heat-labile enterotoxin | GD3(NeuAc) | Disialoglycosphingolipids | NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 12628483 | |
| Clostridium tetani | Tetanus toxin (C-fragment) | GD1b | Disialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 9038159 | |
| Clostridium tetani | Tetanus toxin | GD1b | Disialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 7527546 | |
| Influenza virus | Unknown | GD1a | Disialoglycosphingolipids | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 7870741 |
