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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name ▼ | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Clostridium botulinum | Botulinum neurotoxin (16S) | Glucose | Monosaccharides | Intestinal epithelial cells (T84) | Glc | Not Binding | 17156748 |
| Clostridium botulinum | HA | Glucose | Monosaccharides | Intestinal epithelial cells (T84) | Glc | Not Binding | 17156748 |
| Neisseria gonorrhoeae | N-methylphenyl-alanine pili | Glucosamine-galactose carbohydrate | Disaccharides | Binding | 12640357 | ||
| Escherichia coli | P-pili | Globo-series GSL | Glycosphingolipids | Uroepithelial cells, Erythrocytes | Gal(a1-4)Gal | Binding | 9973330 |
| Escherichia coli | PapG | Globo-series GSL | Glycosphingolipids | Uroepithelial cells, Erythrocytes | Gal(a1-4)Gal | Binding | 9973330 |
| Escherichia coli | (class I/II/III) | Globo-A | Oligoglycosylceramides | Binding | 7721812 | ||
| Escherichia coli | P-fimbriae | Globo-A | Oligoglycosylceramides | Binding | 7721812 | ||
| Escherichia coli | NeuC protein of K1 capsule (UDP GlcNAc 2-epimerase)) | GlcNAc-6-P | Saccharides | Not Binding | 14729696 | ||
| Streptococcus pneumoniae | Adhesins | GlcNAc(b1-3)Gal sequence | Saccharides | Human endothelial cells | GlcNAc(b1-3)Gal | Binding | 6886624 |
| Escherichia coli | 20K-fimbriae | GlcNAc sequence | Saccharides | Human colon carcinoma Caco-2 cell line | GlcNAc | Binding | 8557360 |
| Escherichia coli | K88ab | GlcNAc residues in the core of N-glycan on pSTf (porcine serum transferrin) | N-glycans | Porcine serum | Binding | 11953368 | |
| Helicobacter pylori | 35S-labeled or 125I-labeled proteins | GgO4 (de-N-acylated) | Oligoglycosylceramides | Mouse small intestine | Gal(b1-3)GalNH2(b1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9499377 |
| Helicobacter pylori | 35S-labeled or 125I-labeled proteins | GgO3 (de-N- acylated) | Oligoglycosylceramides | Guinea pig erythrocytes | GalNH2(b1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9499377 |
| Escherichia coli | PrsG (class III) G adhesins | Gb5 (Forssman glycolipid) | Oligoglycosylceramides | Acute cystitis patients | GalNAc(a1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | |
| Streptococcus pneumoniae | Adhesins | Gb5 (Forssman glycolipid) | Oligoglycosylceramides | Type-II lung cells, Vascular endothelial cells | GalNAc(a1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 7752878 |
| Escherichia coli | P-fimbriae | Gb5 (Forssman glycolipid) | Oligoglycosylceramides | Acute cystitis patients | GalNAc(a1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | |
| Escherichia coli | PapG (class III) | Gb5 (Forssman glycolipid) | Oligoglycosylceramides | GalNAc(a1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 11454740 | |
| Escherichia coli | (class I/II/III) | Gb5 (Forssman glycolipid) | Oligoglycosylceramides | GalNAc(a1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 7721812 | |
| Escherichia coli | P-fimbriae | Gb5 (Forssman glycolipid) | Oligoglycosylceramides | GalNAc(a1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 7721812 | |
| Escherichia coli | P-pili | Gb5 (Forssman glycolipid) | Oligoglycosylceramides | GalNAc(a1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 11454740 | |
| Escherichia coli | P-pili | Gb5 (Forssman glycolipid) | Oligoglycosylceramides | GalNAc(a1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 11953368 | |
| Escherichia coli | (class III) | Gb5 (Forssman glycolipid) | Oligoglycosylceramides | GalNAc(a1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 11953368 | |
| Escherichia coli | P adhesin (PapG AD110 type) | Gb5 (Forssman glycolipid) | Oligoglycosylceramides | GalNAc(a1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 8440715 | |
| Escherichia coli | Unknown | Gb5 (Forssman glycolipid) | Oligoglycosylceramides | GalNAc(a1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 2435422 | |
| Helicobacter pylori | 35S-labeled or 125I-labeled proteins | Gb5 (Forssman glycolipid) | Oligoglycosylceramides | Dog small intestine | GalNAc(a1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9499377 |
