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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding ▲ | PubMed ID |
|---|---|---|---|---|---|---|---|
| Influenza virus | Unknown | Neuraminic acid | Monosaccharides | Binding | 8574698 | ||
| Helicobacter pylori | Unknown | Sialic acid | Monosaccharides | Binding | 8574698 | ||
| Newcastle disease virus | HN(hemagglutinin-neuraminidase) glycoproteins | Sialic acid | Monosaccharides | Binding | 17205603 | ||
| Sendai virus | "HN (hemagglutinin neuraminidase), F (fusion protein)" | Sialic acid | Monosaccharides | Binding | 8574698 | ||
| Rotavirus | VP8 (galectin) | Sialic acid(2-O-methyl-α-Neu5Ac (Neu5Ac2Me)) | Monosaccharides | Binding | 17306299 | ||
| Rotavirus | VP8 (spike protein) | Sialic acid | Monosaccharides | Binding | 17277447 | ||
| Rotavirus | VP8 | Sialic acid | Monosaccharides | Binding | 18540062 | ||
| Helicobacter pylori | Unknown | Sialic acid | Monosaccharides | Binding | 16088272 | ||
| Rotavirus | TLP (Triple-layered virus particles) | Gangliosides | Sialoglycosphingolipids | Binding | 10659372 | ||
| Borrelia burgdorferi | "OspA, OspB, OspC" | Gangliosides | Sialoglycosphingolipids | Binding | 16299269 | ||
| Influenza virus | Unknown | Neuraminic acid-containing sialoglycosphingolipids | Sialoglycosphingolipids | Binding | 15973004 | ||
| Burkholderia cepacia | Lectin-like proteins (adhesin) | Gb2 (Galabiosylceramide) | Diosylceramides | Sputa of cystic fibrosis patients | Gal(a1-4)Gal(b1-1)Cer | Binding | 8606110 |
| Bordetella pertussis | CRD (carbohydrate recognition domain) of Fha (Filamentous Hemagglutinin) | Lactosylceramide (Lactocerebroside) | Diosylceramides | Respiratory ciliated cells, Alveolar macrophages | Gal(b1-4)Glc(b1-1)Cer | Binding | 8514379 |
| Escherichia coli | S-fimbriae (SfaA) | Lactosylceramide (Lactocerebroside) | Diosylceramides | Brain endothelial cells | Gal(b1-4)Glc(b1-1)Cer | Binding | 8098039 |
| Escherichia coli | P-fimbriae | Gb2 (Galabiosylceramide) | Diosylceramides | Urine | Gal(a1-4)Gal(b1-1)Cer | Binding | 16564136 |
| Pseudomonas aeruginosa | Type 4-pili | Lactosylceramide (Lactocerebroside) | Diosylceramides | Epithelial cells | Gal(b1-4)Glc(b1-1)Cer | Binding | 9224879 |
| Escherichia coli | P-pili | Gb2 (Galabiosylceramide) | Diosylceramides | Epithelial cells in human urinary tract | Gal(a1-4)Gal(b1-1)Cer | Binding | 9007266 |
| Bordetella pertussis | Pertussis toxin | Lactosylceramide (Lactocerebroside) | Diosylceramides | Human cilia of the respiratory epithelium | Gal(b1-4)Glc(b1-1)Cer | Binding | 1729677 |
| Saccharomyces cerevisiae | Unknown | Lactosylceramide (Lactocerebroside) | Diosylceramides | Human lung, Human polymorphonuclear leukocytes, Human glioma brain cells | Gal(b1-4)Glc(b1-1)Cer | Binding | 2194958 |
| Propionibacterium granulosum | Unknown | Lactosylceramide (Lactocerebroside) | Diosylceramides | Whole dog small intestine | Gal(b1-4)Glc(b1-1)Cer | Binding | 2452754 |
| Helicobacter pylori | 35S-labeled or 125I-labeled proteins | Lactosylceramide (d18:1-h16:0/t18:0-h24:0/t18:0-h16:0) | Diosylceramides | Dog small intestine | Gal(b1-4)Glc(b1-1)Cer | Binding | 9499377 |
| Sporothrix schenckii | Unknown | Lactosylceramide (Lactocerebroside) | Diosylceramides | Human lung, Human polymorphonuclear leukocytes | Gal(b1-4)Glc(b1-1)Cer | Binding | 2194958 |
| Candida albicans | Unknown | Lactosylceramide (Lactocerebroside) | Diosylceramides | Human lung, Human polymorphonuclear leukocytes, Human glioma brain cells | Gal(b1-4)Glc(b1-1)Cer | Binding | 2194958 |
| Bordetella pertussis | FHA (1141-1279) | Lactosylceramide (Lactocerebroside) | Diosylceramides | Ciliated epithelium of the respiratory tract | Gal(b1-4)Glc(b1-1)Cer | Binding | 11348687 |
| Histoplasma capsulatum | Adhesins | Lactosylceramide (Lactocerebroside) | Diosylceramides | Phagocytes | Gal(b1-4)Glc(b1-1)Cer | Binding | 19547878 |
