Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding ▲ | PubMed ID |
|---|---|---|---|---|---|---|---|
| Enterococcus faecalis | EfaA (Lary family) | D-Galactose-containing residues | Saccharides | Gal | Binding | 12640357 | |
| Escherichia coli | P-fimbriae | GL-IV glycolipid | Glycolipids | Binding | 7721812 | ||
| Escherichia coli | (class II) | GL-II glycolipid | Glycolipids | Binding | 7721812 | ||
| Escherichia coli | (class I/II) | GL-IV glycolipid | Glycolipids | Binding | 7721812 | ||
| Escherichia coli | P-fimbriae | GL-II glycolipid | Glycolipids | Binding | 7721812 | ||
| Escherichia coli | (class I/II) | GL-III glycolipid | Glycolipids | Binding | 7721812 | ||
| Escherichia coli | P-fimbriae | GL-III glycolipid | Glycolipids | Binding | 7721812 | ||
| Streptococcus pneumoniae | SpsA | IgA | Glycoproteins | Binding | 10341176 | ||
| Escherichia coli | CsgA (curli) | Human contact phase proteins | Glycoproteins | Binding | 9973330 | ||
| Escherichia coli | Type 1-fimbriae | alpha-Mannosyl groups on glycoproteins | Glycoproteins | Binding | 11454740 | ||
| Bordetella pertussis | Pertussis toxin | Haptoglobin | Glycoproteins | Binding | 1729677 | ||
| Salmonella enteritidis | AgfA (curli) | Human contact phase proteins | Glycoproteins | Binding | 9973330 | ||
| Streptococcus pneumoniae | PspC (Lary family) (alias: SpsA/CbpA/PbcA/Hic) | IgA | Glycoproteins | Binding | 12640357 | ||
| Fusobacterium nucleatum | Lectin-like proteins (adhesin) | Mr 36,900 PRG (Proline-Rich Glycoprotein) | Glycoproteins | Binding | 1894623 | ||
| Staphylococcus epidermidis | 17-kDa HBP (Heparin-binding protein) | Thrombospondin (TSP) | Glycoproteins | Binding | 11393292 | ||
| Fusobacterium nucleatum | Lectin-like proteins (adhesin) | Mr 89,000 PRG (Proline-Rich Glycoprotein) | Glycoproteins | Binding | 1894623 | ||
| Bordetella pertussis | PT (subunit S2 of B oligomer) | Haptoglobin | Glycoproteins | Binding | 1729677 | ||
| Staphylococcus haemolyticus | 17-kDa HBP (Heparin-binding protein) | Thrombospondin (TSP) | Glycoproteins | Binding | 11393292 | ||
| Rotavirus | DLP (Double-layered virus particles) | Asialo gangliosides | Neutral Glycosphingolipids | Binding | 10659372 | ||
| New world arenavirus | Glycoprotein (GP) | O-mannosyl glycans on alpha-dystroglycan (DG) | O-glycans | Binding | 17360738 | ||
| Escherichia coli | hLT | Blood group A antigen analog | Oligosaccharides | Binding | 18809496 | ||
| Borrelia burgdorferi | "DbpA, DbpB, Bgp" | Decorin | Proteoglycans | Binding | 16299269 | ||
| Anaplasma marginale | "MSP1a, MSP1b, MSP2" | unknown carbohydrate ligand | Saccharides | Binding | 16299269 | ||
| Legionella pneumophila | Adhesins | GD1a | Disialoglycosphingolipids | Human epithelial cells (respiratory tract) | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Not Binding | 14687561 |
| Actinomyces viscosus | Unknown | GD1a | Disialoglycosphingolipids | Human brain | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
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