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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence ▼ | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Escherichia coli | 18-kDa fimbrial adhesin | Galactose derivatives | Saccharides | HEp-2 cells | Gal | Binding | 11368522 |
| Bordetella pertussis | FHA (filamentous hemagglutinin) | Galactose on sulfated glycolipids | Glycolipids | Gal | Binding | 12640357 | |
| Pseudomonas aeruginosa | PA-IL (51-kDa) | D-Galactose | Monosaccharides | Gal | Binding | 15049333 | |
| Pseudomonas aeruginosa | PA-I | Galactose | Monosaccharides | Gal | Binding | 8574698 | |
| Entamoeba histolytica | Membrane-associated lectins (heavy(170-kDa)/light(35-or31-kDa) subunits) | Galactose | Monosaccharides | Gal | Binding | 10225860 | |
| Pseudomonas aeruginosa | PA-IL | Galactose | Monosaccharides | Gal | Binding | 10967261 | |
| Escherichia coli | Unknown | Galactose | Monosaccharides | Gal | Binding | 2885220 | |
| Entamoeba histolytica | 52-kDa recombinant fusion proteins | Galactose | Monosaccharides | Gal | Binding | 8574698 | |
| Clostridium difficile | Toxin A | β-Gal on Fab of IgG3(λ) MAb | Glycoproteins | Mouse | Gal | Binding | 9573079 |
| Clostridium difficile | Unknown | β-Gal on Fab of IgG3(λ) MAb | Glycoproteins | Mouse | Gal | Binding | 9573079 |
| Pseudomonas aeruginosa | PA-IIL | L-Galactose | Monosaccharides | Gal | Binding | 10967261 | |
| Enterococcus faecalis | EfaA (Lary family) | D-Galactose-containing residues | Saccharides | Gal | Binding | 12640357 | |
| Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | unnamed ligand | Sialoglycosphingolipids | Human erythrocytes | Fuc(a1-2)Gal(b1-4)GlcNAc(b1-6)[NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)]Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9228091 |
| Escherichia coli | K88ab/K88ac/K88ad | Fuc-nLc6 (VI2) | Oligoglycosylceramides | Fuc(a1-2)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11953368 | |
| Escherichia coli | F1C | H5 type 2 pentaglycosylceramide (neolacto-series) | Oligoglycosylceramides | Human erythrocytes | Fuc(a1-2)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11877427 |
| Neisseria gonorrhoeae | Lectin-like proteins (adhesin) | H5 type 2 pentaglycosylceramide (neolacto-series) | Oligoglycosylceramides | Gonorrhoeae patients | Fuc(a1-2)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2468365 |
| Propionibacterium granulosum | Lectin-like proteins (adhesin) | H5 type 2 pentaglycosylceramide (neolacto-series) | Oligoglycosylceramides | Human skin | Fuc(a1-2)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2468365 |
| Lactobacillus johnsonii | Unknown | H5 type 2 pentaglycosylceramide (neolacto-series) | Oligoglycosylceramides | Human erythrocytes | Fuc(a1-2)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11087711 |
| Vibrio cholerae | Cholera toxin | H5 type 2 pentaglycosylceramide (neolacto-series) | Oligoglycosylceramides | Fuc(a1-2)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7527546 | |
| Escherichia coli | Heat-labile enterotoxin | H5 type 2 pentaglycosylceramide (neolacto-series) | Oligoglycosylceramides | Fuc(a1-2)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7527546 | |
| Vibrio cholerae | Unknown | H5 type 2 pentaglycosylceramide (neolacto-series) | Oligoglycosylceramides | Fuc(a1-2)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7527546 | |
| Escherichia coli | Unknown | H5 type 2 pentaglycosylceramide (neolacto-series) | Oligoglycosylceramides | Fuc(a1-2)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7527546 | |
| Propionibacterium freudenreichii | Unknown | H5 type 2 pentaglycosylceramide (neolacto-series) | Oligoglycosylceramides | Fuc(a1-2)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2435422 | |
| Propionibacterium granulosum | Unknown | H5 type 2 pentaglycosylceramide (neolacto-series) | Oligoglycosylceramides | Fuc(a1-2)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2435422 | |
| Actinomyces viscosus | Unknown | unnamed ligand | Oligoglycosylceramides | Dog small intestine | Fuc(a1-2)Gal(b1-4)GlcNAc(b1-3)Gal(b1-3)Glc(b1-1)Cer | Not Binding | 2358461 |
