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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding ▲ | PubMed ID |
|---|---|---|---|---|---|---|---|
| Neisseria gonorrhoeae | Lectin-like proteins (adhesin) | Lewis a (Lea) (GSL) | Glycosphingolipids | Gonorrhoeae patients | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2468365 |
| Actinomyces viscosus | Unknown | unnamed ligand | Glycosphingolipids | Human meconium | Fuc(a1-2)Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Lactobacillus johnsonii | Unknown | Lewis a (Lea) (GSL) | Glycosphingolipids | Human small intestine | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11087711 |
| Shigella dysenteriae | B subunit | unnamed ligand | Glycosphingolipids | Human meconium | Fuc(a1-2)Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 3543013 |
| Actinomyces naeslundii | Unknown | unnamed ligand | Glycosphingolipids | Human meconium | Fuc(a1-2)Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Escherichia coli | PrsG (class III) | Glucosylceramide | Monoglycosylceramides | Colonic adenocarcinoma | Glc(b1-1)Cer | Not Binding | 9673272 |
| Escherichia coli | PapG (class I) | Glucosylceramide | Monoglycosylceramides | Colonic adenocarcinoma | Glc(b1-1)Cer | Not Binding | 9673272 |
| Escherichia coli | P-fimbriae | Glucosylceramide | Monoglycosylceramides | Colonic adenocarcinoma | Glc(b1-1)Cer | Not Binding | 9673272 |
| Helicobacter pylori | 35S-labeled or 125I-labeled proteins | Glucosylceramide | Monoglycosylceramides | Various sources | Glc(b1-1)Cer | Not Binding | 9499377 |
| Escherichia coli | PapG (class II) | Glucosylceramide | Monoglycosylceramides | Colonic adenocarcinoma | Glc(b1-1)Cer | Not Binding | 9673272 |
| Escherichia coli | F1C | Glucosylceramide (d18:1/t18:0-16:0-24:0) | Monoglycosylceramides | Porcine kidney | Glc(b1-1)Cer | Not Binding | 11877427 |
| Escherichia coli | F1C | Galactosylceramide (d18:1-h18:0-h24:0) | Monoglycosylceramides | Sigma | Gal(b1-1)Cer | Not Binding | 11877427 |
| Neisseria gonorrhoeae | Lectin-like proteins (adhesin) | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Gonorrhoeae patients | Gal(b1-1)Cer | Not Binding | 2468365 |
| Neisseria gonorrhoeae | Lectin-like proteins (adhesin) | Glucosylceramide | Monoglycosylceramides | Gonorrhoeae patients | Glc(b1-1)Cer | Not Binding | 2468365 |
| Actinomyces viscosus | Unknown | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Most tissues | Gal(b1-1)Cer | Not Binding | 2358461 |
| Actinomyces viscosus | Unknown | Glucosylceramide | Monoglycosylceramides | Most tissues | Glc(b1-1)Cer | Not Binding | 2358461 |
| Mycoplasma pneumoniae | Unknown | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Human colon adenocarcinoma cells (WiDr ) | Gal(b1-1)Cer | Not Binding | 2470753 |
| Actinomyces naeslundii | Unknown | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Most tissues | Gal(b1-1)Cer | Not Binding | 2358461 |
| Actinomyces naeslundii | Unknown | Glucosylceramide | Monoglycosylceramides | Most tissues | Glc(b1-1)Cer | Not Binding | 2358461 |
| Clostridium botulinum | Botulinum neurotoxin (16S) | N-Acetylglucosamine | Monosaccharides | Intestinal epithelial cells (T84) | GlcNAc | Not Binding | 17156748 |
| Clostridium botulinum | Botulinum neurotoxin (16S) | Mannose | Monosaccharides | Intestinal epithelial cells (T84) | Man | Not Binding | 17156748 |
| Clostridium botulinum | Botulinum neurotoxin (16S) | Glucose | Monosaccharides | Intestinal epithelial cells (T84) | Glc | Not Binding | 17156748 |
| Clostridium botulinum | Botulinum neurotoxin (16S) | Fucose | Monosaccharides | Intestinal epithelial cells (T84) | Fuc | Not Binding | 17156748 |
| Clostridium botulinum | HA | N-Acetylglucosamine | Monosaccharides | Intestinal epithelial cells (T84) | GlcNAc | Not Binding | 17156748 |
| Clostridium botulinum | HA | Mannose | Monosaccharides | Intestinal epithelial cells (T84) | Man | Not Binding | 17156748 |
