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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding ▼ | PubMed ID |
|---|---|---|---|---|---|---|---|
| Rotavirus | VP8 (spike protein) | Sialic acid | Monosaccharides | Binding | 17277447 | ||
| Helicobacter pylori | Unknown | Sialic acid | Monosaccharides | Binding | 16088272 | ||
| Rotavirus | VP8 | Sialic acid | Monosaccharides | Binding | 18540062 | ||
| Sendai virus | "HN (hemagglutinin neuraminidase), F (fusion protein)" | Sialic acid | Monosaccharides | Binding | 8574698 | ||
| Newcastle disease virus | HN(hemagglutinin-neuraminidase) glycoproteins | Sialic acid | Monosaccharides | Binding | 17205603 | ||
| Influenza virus | Unknown | Neuraminic acid | Monosaccharides | Binding | 8574698 | ||
| Helicobacter pylori | Unknown | Sialic acid | Monosaccharides | Binding | 8574698 | ||
| Rotavirus | TLP (Triple-layered virus particles) | Gangliosides | Sialoglycosphingolipids | Binding | 10659372 | ||
| Borrelia burgdorferi | "OspA, OspB, OspC" | Gangliosides | Sialoglycosphingolipids | Binding | 16299269 | ||
| Influenza virus | Unknown | Neuraminic acid-containing sialoglycosphingolipids | Sialoglycosphingolipids | Binding | 15973004 | ||
| Streptococcus suis | Adhesins | Gb2 (Galabiosylceramide) | Diosylceramides | Gal(a1-4)Gal(b1-1)Cer | Binding | 7961660 | |
| Escherichia coli | P-fimbriae | Gb2 (Galabiosylceramide) | Diosylceramides | Gal(a1-4)Gal(b1-1)Cer | Binding | 7721812 | |
| Shigella dysenteriae | Shiga toxin | Gb2 (Galabiosylceramide) | Diosylceramides | Gal(a1-4)Gal(b1-1)Cer | Binding | 2435422 | |
| Shigella dysenteriae | Shiga toxin | Gb2 (Galabiosylceramide) | Diosylceramides | Gal(a1-4)Gal(b1-1)Cer | Binding | 12628483 | |
| Escherichia coli | Unknown | Gb2 (Galabiosylceramide) | Diosylceramides | Gal(a1-4)Gal(b1-1)Cer | Binding | 2435422 | |
| Shigella dysenteriae | Unknown | Gb2 (Galabiosylceramide) | Diosylceramides | Gal(a1-4)Gal(b1-1)Cer | Binding | 2435422 | |
| Shigella dysenteriae | Unknown | Gb2 (Galabiosylceramide) | Diosylceramides | Gal(a1-4)Gal(b1-1)Cer | Binding | 12628483 | |
| Streptococcus pneumoniae | Adhesins | unnamed ligand | Disaccharides | GalNAc(b1-4)Gal | Binding | 6886624 | |
| Pseudomonas aeruginosa | Pili | unnamed ligand | Disaccharides | GalNAc(b1-4)Gal | Binding | 8574698 | |
| Actinomyces naeslundii | Unknown | unnamed ligand | Disaccharides | GalNAc(b1-3)Gal | Binding | 12628483 | |
| Streptococcus gordonii | Ca2+-independent lectins | Hs antigen | Glycoproteins | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc-HSA | Binding | 9393794 | |
| Helicobacter pylori | BabA (blood group antigen binding adhesin) | Blood group H1 antigen (HSA) | Glycoproteins | Fuc(a1-2)Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(c)-APD | Binding | 15273394 | |
| Streptococcus suis | Unknown | Neoglycoproteins (containing P1 Antigen) | Glycoproteins | Gal(a1-4)Gal(b1-4)GlcNAc | Binding | 8440715 | |
| Pseudomonas aeruginosa | PA-IIL | Lewis a (Lea) (GSL) | Glycosphingolipids | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 16762477 | |
| Norovirus | Unknown | Lewis a (Lea) (GSL) | Glycosphingolipids | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 18701592 |
