PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
Source | Last Updated |
---|---|
Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence ▲ | Binding | PubMed ID |
---|---|---|---|---|---|---|---|
Helicobacter canis | Lectin-hemagglutinin adhesins | isoGb3 (Isoglobotriaosylceramide; iGb3) | Oligoglycosylceramides | Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 12704182 | |
Propionibacterium granulosum | Unknown | isoGb3 (Isoglobotriaosylceramide; iGb3) | Oligoglycosylceramides | Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2435422 | |
Shigella dysenteriae | B subunit | isoGb3 (Isoglobotriaosylceramide; iGb3) | Oligoglycosylceramides | Dog small intestine | Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 3543013 |
Shigella dysenteriae | Shiga toxin | isoGb3 (Isoglobotriaosylceramide; iGb3) | Oligoglycosylceramides | Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2435422 | |
Rotavirus | Unknown | isoGb3 (Isoglobotriaosylceramide; iGb3) | Oligoglycosylceramides | Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11160731 | |
Escherichia coli | Unknown | isoGb3 (Isoglobotriaosylceramide; iGb3) | Oligoglycosylceramides | Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2435422 | |
Shigella dysenteriae | Unknown | isoGb3 (Isoglobotriaosylceramide; iGb3) | Oligoglycosylceramides | Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2435422 | |
Propionibacterium freudenreichii | Unknown | isoGb3 (Isoglobotriaosylceramide; iGb3) | Oligoglycosylceramides | Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2435422 | |
Clostridium difficile | Toxin A | unnamed ligand | Oligosaccharides | Human colonic cells | Gal(a1-3)Gal(b1-4)GlcNAc | Binding | 12507507 |
Clostridium difficile | C-terminal domain of toxin A molecules | unnamed ligand | Oligosaccharides | Human colonic cells | Gal(a1-3)Gal(b1-4)GlcNAc | Binding | 12507507 |
Mycoplasma pneumoniae | Unknown | Alpha-Galactosyl paragloboside | Oligoglycosylceramides | Human colon adenocarcinoma cells (WiDr ) | Gal(a1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2470753 |
Escherichia coli | F1C | Alpha-Galactosyl paragloboside | Oligoglycosylceramides | Rabbit erythrocytes | Gal(a1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11877427 |
Lactobacillus johnsonii | Unknown | Alpha-Galactosyl paragloboside | Oligoglycosylceramides | Rabbit erythrocytes | Gal(a1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11087711 |
Shigella dysenteriae | B subunit | Alpha-Galactosyl paragloboside | Oligoglycosylceramides | Rabbit erythrocytes | Gal(a1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 3543013 |
Rotavirus | Unknown | Alpha-Galactosyl paragloboside | Oligoglycosylceramides | Gal(a1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11160731 | |
Mycoplasma pneumoniae | Unknown | I-active Gal2-lactoisooctaosylceramide | Oligoglycosylceramides | Human colon adenocarcinoma cells (WiDr ) | Gal(a1-3)Gal(b1-4)GlcNAc(b1-6)[Gal(a1-3)Gal(b1-4)GlcNAc(b1-3)]Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2470753 |
Rotavirus | Unknown | I-active Sialyl lactoisooctaosylceramide | Sialoglycosphingolipids | Gal(a1-3)Gal(b1-4)GlcNAc(b1-6)[NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)]Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 11160731 | |
Mycoplasma pneumoniae | Unknown | I-active Sialyl lactoisooctaosylceramide | Sialoglycosphingolipids | Human colon adenocarcinoma cells (WiDr ) | Gal(a1-3)Gal(b1-4)GlcNAc(b1-6)[NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)]Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2470753 |
Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | I-active Sialyl lactoisooctaosylceramide | Sialoglycosphingolipids | Bovine erythrocytes | Gal(a1-3)Gal(b1-4)GlcNAc(b1-6)[NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)]Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9228091 |
Norovirus | Unknown | Blood group B antigen | Oligosaccharides | Saliva | Gal(a1-3)[Fuc(a1-2)]Gal | Binding | 18701592 |
Pseudomonas aeruginosa | PA-IIL | Blood group B antigen | Oligosaccharides | Gal(a1-3)[Fuc(a1-2)]Gal | Binding | 16762477 | |
Ralstonia solanacearum | RSL (30-kDa proteins) | Blood group B antigen | Oligosaccharides | Gal(a1-3)[Fuc(a1-2)]Gal | Binding | 16762477 | |
Norovirus | Capsid proteins | Blood group B antigen | Oligosaccharides | Gal(a1-3)[Fuc(a1-2)]Gal | Binding | 18809496 | |
Norovirus | Unknown | Blood group B antigen | Oligosaccharides | Gal(a1-3)[Fuc(a1-2)]Gal | Binding | 18599458 | |
Streptococcus pneumoniae | FcsSBP (fucose solute-binding protein) | Blood group B antigen | Oligosaccharides | Gal(a1-3)[Fuc(a1-2)]Gal | Binding | 19285508 |
GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.
Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01
GlyCosmos Portal v4.0.0
Last updated: August 19, 2024