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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence ▲ | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Helicobacter canis | Lectin-hemagglutinin adhesins | isoGb3 (Isoglobotriaosylceramide; iGb3) | Oligoglycosylceramides | Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 12704182 | |
| Propionibacterium granulosum | Unknown | isoGb3 (Isoglobotriaosylceramide; iGb3) | Oligoglycosylceramides | Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2435422 | |
| Shigella dysenteriae | B subunit | isoGb3 (Isoglobotriaosylceramide; iGb3) | Oligoglycosylceramides | Dog small intestine | Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 3543013 |
| Shigella dysenteriae | Shiga toxin | isoGb3 (Isoglobotriaosylceramide; iGb3) | Oligoglycosylceramides | Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2435422 | |
| Rotavirus | Unknown | isoGb3 (Isoglobotriaosylceramide; iGb3) | Oligoglycosylceramides | Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11160731 | |
| Escherichia coli | Unknown | isoGb3 (Isoglobotriaosylceramide; iGb3) | Oligoglycosylceramides | Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2435422 | |
| Shigella dysenteriae | Unknown | isoGb3 (Isoglobotriaosylceramide; iGb3) | Oligoglycosylceramides | Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2435422 | |
| Propionibacterium freudenreichii | Unknown | isoGb3 (Isoglobotriaosylceramide; iGb3) | Oligoglycosylceramides | Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2435422 | |
| Clostridium difficile | Toxin A | unnamed ligand | Oligosaccharides | Human colonic cells | Gal(a1-3)Gal(b1-4)GlcNAc | Binding | 12507507 |
| Clostridium difficile | C-terminal domain of toxin A molecules | unnamed ligand | Oligosaccharides | Human colonic cells | Gal(a1-3)Gal(b1-4)GlcNAc | Binding | 12507507 |
| Mycoplasma pneumoniae | Unknown | Alpha-Galactosyl paragloboside | Oligoglycosylceramides | Human colon adenocarcinoma cells (WiDr ) | Gal(a1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2470753 |
| Escherichia coli | F1C | Alpha-Galactosyl paragloboside | Oligoglycosylceramides | Rabbit erythrocytes | Gal(a1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11877427 |
| Lactobacillus johnsonii | Unknown | Alpha-Galactosyl paragloboside | Oligoglycosylceramides | Rabbit erythrocytes | Gal(a1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11087711 |
| Shigella dysenteriae | B subunit | Alpha-Galactosyl paragloboside | Oligoglycosylceramides | Rabbit erythrocytes | Gal(a1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 3543013 |
| Rotavirus | Unknown | Alpha-Galactosyl paragloboside | Oligoglycosylceramides | Gal(a1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11160731 | |
| Mycoplasma pneumoniae | Unknown | I-active Gal2-lactoisooctaosylceramide | Oligoglycosylceramides | Human colon adenocarcinoma cells (WiDr ) | Gal(a1-3)Gal(b1-4)GlcNAc(b1-6)[Gal(a1-3)Gal(b1-4)GlcNAc(b1-3)]Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2470753 |
| Mycoplasma pneumoniae | Unknown | I-active Sialyl lactoisooctaosylceramide | Sialoglycosphingolipids | Human colon adenocarcinoma cells (WiDr ) | Gal(a1-3)Gal(b1-4)GlcNAc(b1-6)[NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)]Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2470753 |
| Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | I-active Sialyl lactoisooctaosylceramide | Sialoglycosphingolipids | Bovine erythrocytes | Gal(a1-3)Gal(b1-4)GlcNAc(b1-6)[NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)]Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9228091 |
| Rotavirus | Unknown | I-active Sialyl lactoisooctaosylceramide | Sialoglycosphingolipids | Gal(a1-3)Gal(b1-4)GlcNAc(b1-6)[NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)]Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 11160731 | |
| Norovirus | Unknown | Blood group B antigen | Oligosaccharides | Saliva | Gal(a1-3)[Fuc(a1-2)]Gal | Binding | 18701592 |
| Norovirus | Unknown | Blood group B antigen | Oligosaccharides | Human saliva | Gal(a1-3)[Fuc(a1-2)]Gal | Not Binding | 16707048 |
| Norovirus | Unknown | Blood group B antigen | Oligosaccharides | Saliva | Gal(a1-3)[Fuc(a1-2)]Gal | Not Binding | 18701592 |
| Pseudomonas aeruginosa | PA-IIL | Blood group B antigen | Oligosaccharides | Gal(a1-3)[Fuc(a1-2)]Gal | Binding | 16762477 | |
| Ralstonia solanacearum | RSL (30-kDa proteins) | Blood group B antigen | Oligosaccharides | Gal(a1-3)[Fuc(a1-2)]Gal | Binding | 16762477 | |
| Norovirus | Capsid proteins | Blood group B antigen | Oligosaccharides | Gal(a1-3)[Fuc(a1-2)]Gal | Binding | 18809496 |
