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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name ▼ | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Helicobacter pylori | Unknown | Fucose | Monosaccharides | Fuc | Binding | 16088272 | |
| Clostridium botulinum | Botulinum neurotoxin (16S) | Fucose | Monosaccharides | Intestinal epithelial cells (T84) | Fuc | Not Binding | 17156748 |
| Clostridium botulinum | HA | Fucose | Monosaccharides | Intestinal epithelial cells (T84) | Fuc | Not Binding | 17156748 |
| Escherichia coli | K88ab/K88ac/K88ad | Fuc-nLc6 (VI2) | Oligoglycosylceramides | Fuc(a1-2)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11953368 | |
| Escherichia coli | K88ab/K88ac/K88ad | Fuc-nLc6 (V3) | Oligoglycosylceramides | Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11953368 | |
| Helicobacter pylori | Adhesins | Five-sugar monosialoganglioside | Monosialoglycosphingolipids | Human leukocytes, Human neutrophils | Binding | 10569742 | |
| Sporothrix schenckii | Yeast cells and conidia | Fibronectin | Glycoproteins | Extracellular matrix (ECM) | Binding | 11598061 | |
| Paracoccidioides brasiliensis | Adhesins | Fibronectin | Glycoproteins | Human type II alveolar cells (A549) | Binding | 18083324 | |
| Streptococcus pyogenes | Protein F (Antigen I/II) | Fibronectin | Glycoproteins | Respiratory endothelial cells | Binding | 10341176 | |
| Streptococcus pyogenes | Protein F (Antigen I/II) | Fibronectin | Glycoproteins | Respiratory epithelial cells | Binding | 1385871 | |
| Streptococcus pyogenes | Sfbl (Antigen I/II) | Fibronectin | Glycoproteins | Respiratory endothelial cells | Binding | 10341176 | |
| Streptococcus pyogenes | Sfbl (Antigen I/II) | Fibronectin | Glycoproteins | Respiratory epithelial cells | Binding | 12640357 | |
| Sporothrix schenckii | Yeast cells and hyphae | Fibronectin | Glycoproteins | Extracellular matrix (ECM) | Binding | 15351036 | |
| Streptococcus pyogenes | Protein F (Antigen I/II) | Fibronectin | Glycoproteins | Respiratory epithelial cells | Binding | 12640357 | |
| Staphylococcus aureus | FnbA | Fibronectin | Glycoproteins | Binding | 10341176 | ||
| Streptococcus gordonii | CshB | Fibronectin | Glycoproteins | Binding | 10341176 | ||
| Escherichia coli | FimH | Fibronectin | Glycoproteins | Binding | 12010488 | ||
| Streptococcus gordonii | CshaB (Antigen I/II) | Fibronectin | Glycoproteins | Binding | 12640357 | ||
| Escherichia coli | Type 1-pili | Fibronectin | Glycoproteins | Binding | 12010488 | ||
| Borrelia burgdorferi | BBK32 | Fibronectin | Glycoproteins | Binding | 18833295 | ||
| Staphylococcus aureus | FnbB | Fibronectin | Glycoproteins | Binding | 12640357 | ||
| Staphylococcus aureus | FnbB | Fibronectin | Glycoproteins | Binding | 10341176 | ||
| Staphylococcus aureus | FnbA | Fibronectin | Glycoproteins | Binding | 12640357 | ||
| Streptococcus gordonii | CshA | Fibronectin | Glycoproteins | Binding | 10341176 | ||
| Streptococcus gordonii | CshA (Antigen I/II) | Fibronectin | Glycoproteins | Binding | 12640357 |
