Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence ▲ | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Clostridium tetani | TeNT | Polysialogangliosides and other acidic lipids | Glycolipids | Presynaptic membrane of neuromuscular junction | Binding | 7527117 | |
| Actinomyces naeslundii | Adhesins | PMN (polymorphonuclear leukocytes) surface glycoproteins | Glycoproteins | Human peripheral blood buffy coat cells | Binding | 11035744 | |
| Actinomyces naeslundii | Adhesins | Asialofetuin | Glycoproteins | HL-60 promyelocytic leukemia cell line | Binding | 11035744 | |
| Streptococcus sobrinus | SpaA (Antigen I/II Family) | Salivary glycoprotein | Glycoproteins | Tooth surface | Binding | 10341176 | |
| Streptococcus mutans | P1 (Antigen I/II) | Salivary glycoprotein | Glycoproteins | Saliva | Binding | 12640357 | |
| Streptococcus mutans | P1 (Antigen I/II) | Salivary glycoprotein | Glycoproteins | Tooth surface | Binding | 10341176 | |
| Bordetella pertussis | FHA (tail region) | Complement receptor 3 (CR3) integrins | Glycoproteins | Macrophages | Binding | 11348687 | |
| Shigella dysenteriae | Adhesins | Colonic mucin | Glycoproteins | Colon | Binding | 11381327 | |
| Streptococcus parasanguinis | FimA (Lary family) | Salivary glycoprotein | Glycoproteins | Saliva | Binding | 12640357 | |
| Streptococcus sanguis | SsaB (Lral family) | Salivary glycoprotein | Glycoproteins | Tooth surface | Binding | 10341176 | |
| Streptococcus sanguis | SsaB (Lary family) | Salivary glycoprotein | Glycoproteins | Saliva | Binding | 12640357 | |
| Streptococcus gordonii | SspA/SspB (AgI/II family) | Collagen (type I) | Glycoproteins | humHn oral cavity (root dentine) | Binding | 16177339 | |
| Streptococcus gordonii | SspA/SspB (AgI/II family) | Salivary glycoprotein (gp340) | Glycoproteins | Human oral cavity (in fluid and surface-associated phases) | Binding | 16177339 | |
| Helicobacter pylori | Adhesins | Fetuin | Glycoproteins | Human leukocytes, Human neutrophils | Binding | 10569742 | |
| Escherichia coli | K99 | Mucin | Glycoproteins | Intestinal cells | Binding | 7849044 | |
| Neisseria meningitidis | Type 4-pili | Thyroglobulin containing N-linked complex and hybrid (oligomannosidic) glycans | Glycoproteins | Bovine | Binding | 16177210 | |
| Bordetella pertussis | Pertussis toxin | Fetuin | Glycoproteins | Bovine | Binding | 14532091 | |
| Helicobacter pylori | Unknown | Salivary glycoprotein (gp340) | Glycoproteins | Human stomach associated with gastritis and peptic ulcer disease | Binding | 11007786 | |
| Foot-and-mouth disease virus | VP1 (RGD peptide) | αvβ3 Integrin (independent of expression of Heparan sulfate on cell-sulface) | Glycoproteins | Extracellular matrix (ECM) | Binding | 9557639 | |
| Foot-and-mouth disease virus | RGD motif of the VP1 GH loop | αvβ6 Integrin | Glycoproteins | Epithelial cells | Binding | 10799568 | |
| Streptococcus agalactiae | Unknown | Salivary glycoprotein (gp340) | Glycoproteins | Neonatal meningitis | Binding | 11007786 | |
| Pseudomonas aeruginosa | Adhesins | MUC1 mucin | Glycoproteins | Surface of chinese hamster ovary (CHO) cells | Binding | 11133508 | |
| Streptococcus gordonii | SspA (Antigen I/II) | Salivary glycoprotein | Glycoproteins | Saliva | Binding | 12640357 | |
| Streptococcus gordonii | SspA (Antigen I/II) | Salivary glycoprotein | Glycoproteins | Tooth surface | Binding | 10341176 | |
| Streptococcus mutans | SpaP (Antigen I/II Family) | Salivary glycoprotein | Glycoproteins | Saliva | Binding | 12640357 |
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