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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name ▼ | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Mycoplasma gallisepticum | PlpA (pneumoniae-like protein; P65) | Fibronectin | Glycoproteins | Binding | 16495551 | ||
| Escherichia coli | CsgA (curli) | Fibronectin | Glycoproteins | Binding | 9973330 | ||
| Staphylococcus aureus | FnBPB (fibronectin binding protein) | Fibronectin | Glycoproteins | Binding | 1837266 | ||
| Staphylococcus aureus | FnBPA (fibronectin binding protein) | Fibronectin | Glycoproteins | Binding | 1837266 | ||
| Salmonella enteritidis | AgfA (curli) | Fibronectin | Glycoproteins | Binding | 9973330 | ||
| Mycoplasma gallisepticum | Hlp3 (HMW3-like protein) | Fibronectin | Glycoproteins | Binding | 16495551 | ||
| Paracoccidioides brasiliensis | Adhesins | Fibrinogen | Glycoproteins | Human type II alveolar cells (A549) | Binding | 18083324 | |
| Helicobacter pylori | Adhesins | Fetuin | Glycoproteins | Human leukocytes, Human neutrophils | Binding | 10569742 | |
| Bordetella pertussis | Pertussis toxin | Fetuin | Glycoproteins | Bovine | Binding | 14532091 | |
| Mycoplasma pneumoniae | Adhesins | Fetuin | Glycoproteins | Bovine erythrocytes | Binding | 2470754 | |
| Streptococcus gordonii | Adhesins | Fetuin | Glycoproteins | HL-60 promyelocytic leukemia cell line | Binding | 11035744 | |
| Bordetella pertussis | Unknown | Fetuin | Glycoproteins | Bovine | Binding | 14532091 | |
| Streptococcus gordonii | Ca2+-independent lectins | Fetuin | Glycoproteins | Binding | 9393794 | ||
| Bordetella pertussis | Pertussis toxin | Fetuin | Glycoproteins | Binding | 1729677 | ||
| Bordetella pertussis | PT (subunit S2 of B oligomer) | Fetuin | Glycoproteins | Binding | 1729677 | ||
| Influenza virus | Unknown | Fetuin | Glycoproteins | Not Binding | 1740131 | ||
| Vibrio cholerae | Cholera toxin | Extended GM1 | Monosialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 7527546 | |
| Vibrio cholerae | Unknown | Extended GM1 | Monosialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 7527546 | |
| Helicobacter pylori | Unknown | Epithelial type of glycolipid containing 2-hydroxy fatty acid | Glycolipids | Binding | 8574698 | ||
| Influenza virus | Unknown | Endothelial cell-specific molecule (ESM) | Proteoglycans | Not Binding | 1740131 | ||
| Escherichia coli | F1C | Disialosyl lacto-N-nor-hexaosylceramide (DSnHC) | Sialoglycosphingolipids | NeuAc(a2-8)NeuAc(a2-3)[Gal(b1-4)GlcNAc]2(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 10816509 | |
| Bordetella pertussis | FHA (442-863) | Dextran sulfate | Polysaccharides | WiDr cells, HeLa cells, Vero cells, Extracellular matrix (ECM) | Binding | 11348687 | |
| Human immunodeficiency virus | Unknown | Dextran sulfate | Polysaccharides | Human T cells | Binding | 9420059 | |
| Chlamydia trachomatis | Unknown | Dextran sulfate | Polysaccharides | HeLa cells | Binding | 9420059 | |
| Herpes simplex virus | Unknown | Dextran sulfate | Polysaccharides | Human cervical cells | Binding | 9420059 |
