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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding ▼ | PubMed ID |
|---|---|---|---|---|---|---|---|
| Helicobacter pylori | HP0721 | Sialyl Lewis x (SLex) antigen | Oligosaccharides | Gastric epithelial progenitors (GEPs) | NeuAc(a2-3)Gal(b1-4) | Binding | 16406776 |
| Influenza virus | Unknown | NeuAc3-nLc6Cer (Sialyl neolactohexaosylceramide) | Sialoglycosphingolipids | Granulocytes | NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 8823909 |
| Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | NeuAc3-nLc6Cer (Sialyl neolactohexaosylceramide) | Sialoglycosphingolipids | Human erythrocytes, Human placenta | NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 9228091 |
| Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | unnamed ligand | Sialoglycosphingolipids | Human erythrocytes | NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 9228091 |
| Sendai virus | Unknown | NeuAc3-nLc6Cer (Sialyl neolactohexaosylceramide) | Sialoglycosphingolipids | Granulocytes | NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 8823909 |
| Actinomyces naeslundii | Unknown | unnamed ligand | Sialoglycosphingolipids | Frog brain | Gal(b1-3)[NeuAc(a2-6)]GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 2358461 |
| Paramyxovirus | Unknown | 116 kDa glycoprotein (containing sialic acid residues with N-linked glycans) | N-glycans | Neurones of all brain regions | Binding | 11666031 | |
| Polyoma virus | Capsid VP1 | GD1a-GT1b analog | Sialoglycosphingolipids | (broad range) | Binding | 18809496 | |
| Bordetella pertussis | CRD (carbohydrate recognition domain) of Fha (Filamentous Hemagglutinin) | Lactosylceramide (Lactocerebroside) | Diosylceramides | Respiratory ciliated cells, Alveolar macrophages | Gal(b1-4)Glc(b1-1)Cer | Binding | 8514379 |
| Escherichia coli | S-fimbriae (SfaA) | Lactosylceramide (Lactocerebroside) | Diosylceramides | Brain endothelial cells | Gal(b1-4)Glc(b1-1)Cer | Binding | 8098039 |
| Pseudomonas aeruginosa | Type 4-pili | Lactosylceramide (Lactocerebroside) | Diosylceramides | Epithelial cells | Gal(b1-4)Glc(b1-1)Cer | Binding | 9224879 |
| Bordetella pertussis | Pertussis toxin | Lactosylceramide (Lactocerebroside) | Diosylceramides | Human cilia of the respiratory epithelium | Gal(b1-4)Glc(b1-1)Cer | Binding | 1729677 |
| Saccharomyces cerevisiae | Unknown | Lactosylceramide (Lactocerebroside) | Diosylceramides | Human lung, Human polymorphonuclear leukocytes, Human glioma brain cells | Gal(b1-4)Glc(b1-1)Cer | Binding | 2194958 |
| Propionibacterium granulosum | Unknown | Lactosylceramide (Lactocerebroside) | Diosylceramides | Whole dog small intestine | Gal(b1-4)Glc(b1-1)Cer | Binding | 2452754 |
| Sporothrix schenckii | Unknown | Lactosylceramide (Lactocerebroside) | Diosylceramides | Human lung, Human polymorphonuclear leukocytes | Gal(b1-4)Glc(b1-1)Cer | Binding | 2194958 |
| Candida albicans | Unknown | Lactosylceramide (Lactocerebroside) | Diosylceramides | Human lung, Human polymorphonuclear leukocytes, Human glioma brain cells | Gal(b1-4)Glc(b1-1)Cer | Binding | 2194958 |
| Bordetella pertussis | FHA (1141-1279) | Lactosylceramide (Lactocerebroside) | Diosylceramides | Ciliated epithelium of the respiratory tract | Gal(b1-4)Glc(b1-1)Cer | Binding | 11348687 |
| Histoplasma capsulatum | Adhesins | Lactosylceramide (Lactocerebroside) | Diosylceramides | Phagocytes | Gal(b1-4)Glc(b1-1)Cer | Binding | 19547878 |
| Bordetella pertussis | PT (subunit S2 of B oligomer) | Lactosylceramide (Lactocerebroside) | Diosylceramides | Human cilia of the respiratory epithelium | Gal(b1-4)Glc(b1-1)Cer | Binding | 1729677 |
| Neisseria gonorrhoeae | Lectin-like proteins (adhesin) | Lactosylceramide (Lactocerebroside) | Diosylceramides | Gonorrhoeae patients | Gal(b1-4)Glc(b1-1)Cer | Binding | 2468365 |
| Actinomyces viscosus | Unknown | Lactosylceramide (Lactocerebroside) | Diosylceramides | Dog small intestine | Gal(b1-4)Glc(b1-1)Cer | Binding | 2358461 |
| Mycoplasma pneumoniae | Unknown | Lactosylceramide (Lactocerebroside) | Diosylceramides | Human colon adenocarcinoma cells (WiDr ) | Gal(b1-4)Glc(b1-1)Cer | Binding | 2470753 |
| Lactobacillus johnsonii | Unknown | Lactosylceramide (Lactocerebroside) | Diosylceramides | Dog small intestine | Gal(b1-4)Glc(b1-1)Cer | Binding | 11087711 |
| Histoplasma capsulatum | Unknown | Lactosylceramide (Lactocerebroside) | Diosylceramides | Human lung, Human polymorphonuclear leukocytes | Gal(b1-4)Glc(b1-1)Cer | Binding | 2194958 |
| Propionibacterium freudenreichii | Unknown | Lactosylceramide (Lactocerebroside) | Diosylceramides | Human erythrocytes, Whole dog small intestine | Gal(b1-4)Glc(b1-1)Cer | Binding | 2452754 |
