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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence ▲ | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Campylobacter upsaliensis | 5 bacterial surface proteins (50 to 90-kDa) | Phosphatidylethanolamine (PE) | Non-glycosylated Lipids | HEp-2 cells | Binding | 8926069 | |
| Campylobacter upsaliensis | Unknown | Lyso-PE | Non-glycosylated Lipids | HEp-2 cells | Binding | 8926069 | |
| Clostridium botulinum | BoNT/D (two lysine residues (K1117 and K1135 in Hc/D1)) | Phosphatidylethanolamine (PE) | Non-glycosylated Lipids | Presynaptic neuronal cells | Binding | 18242046 | |
| Helicobacter pylori | SabA (sialic acid-binding adhesin) | Fucosylated Lewis b (Leb) histoblood group antigens | Oligosaccharides | Mucosal surface of the gastric epithelium | Binding | 12640357 | |
| Norovirus | Unknown | Blood group O antigen | Oligosaccharides | Human saliva | Binding | 16707048 | |
| Helicobacter pylori | BabA (blood group antigen binding adhesin) | Fucosylated Lewis b (Leb) histoblood group antigens | Oligosaccharides | Human gastric epithelium | Binding | 9430586 | |
| Human immunodeficiency virus | Unknown | N-acetyl-b-maltoheptaosylamine sulfate (SM) | Oligosaccharides | Human T cells | Binding | 9420059 | |
| Chlamydia trachomatis | Unknown | N-acetyl-b-maltoheptaosylamine sulfate (SM) | Oligosaccharides | HeLa cells | Binding | 9420059 | |
| Herpes simplex virus | Unknown | N-acetyl-b-maltoheptaosylamine sulfate (SM) | Oligosaccharides | Human cervical cells | Binding | 9420059 | |
| Bordetella pertussis | FHA (442-863) | Dextran sulfate | Polysaccharides | WiDr cells, HeLa cells, Vero cells, Extracellular matrix (ECM) | Binding | 11348687 | |
| Human immunodeficiency virus | Unknown | Pentosan polysulfate (PP) | Polysaccharides | Human T cells | Binding | 9420059 | |
| Human immunodeficiency virus | Unknown | Dextran sulfate | Polysaccharides | Human T cells | Binding | 9420059 | |
| Chlamydia trachomatis | Unknown | Pentosan polysulfate (PP) | Polysaccharides | HeLa cells | Binding | 9420059 | |
| Chlamydia trachomatis | Unknown | Dextran sulfate | Polysaccharides | HeLa cells | Binding | 9420059 | |
| Herpes simplex virus | Unknown | Pentosan polysulfate (PP) | Polysaccharides | Human cervical cells | Binding | 9420059 | |
| Herpes simplex virus | Unknown | Dextran sulfate | Polysaccharides | Human cervical cells | Binding | 9420059 | |
| Neisseria gonorrhoeae | Unknown | Pentosan polysulfate (PP) | Polysaccharides | Human epithelial cells | Binding | 9420059 | |
| Neisseria gonorrhoeae | Unknown | Dextran sulfate | Polysaccharides | Human epithelial cells | Binding | 9420059 | |
| Norovirus | Unknown | Terminal N-Acetylgalactosamine residue in an alpha linkage | Saccharides | Oyster digestive tissues | Binding | 16707048 | |
| Neisseria gonorrhoeae | N-methylphenyl-alanine pili | Glucosamine-galactose carbohydrate | Disaccharides | Binding | 12640357 | ||
| Streptococcus pneumoniae | PsaA (Lary family) | N-acetylhexosamine-galactose | Disaccharides | Binding | 12640357 | ||
| Helicobacter pylori | Unknown | Epithelial type of glycolipid containing 2-hydroxy fatty acid | Glycolipids | Binding | 8574698 | ||
| Helicobacter pylori | Unknown | Monohexyl ceramides (MHCer) | Glycolipids | Binding | 16088272 | ||
| Streptococcus gordonii | Ca2+-independent lectins | Fetuin | Glycoproteins | Binding | 9393794 | ||
| Escherichia coli | FimH | CD48 | Glycoproteins | Binding | 12010488 |
